Protein: BOREA
Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein)

Gene: BOREA, CDCA8
Organism: Homo sapiens
Interactions: 118
UniProt ID: Q53HL2

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000278 - mitotic cell cycle
GO:0000281 - mitotic cytokinesis
GO:0000775 - chromosome, centromeric region
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1121629

INCE
Inner centromere protein

8

6

Small-scale

0.975

High

177693

BIRC5
Baculoviral IAP repeat-containing protein 5

16

1

Small-scale

0.767

High

1121619

AURKB
Aurora kinase B

14

0

Small-scale

0.730

High

502917

MYH3
Myosin-3

3

3

High-throughput

0.667

High

1050869

DPYL1
Dihydropyrimidinase-related protein 1

3

2

High-throughput

0.667

High

1050920

DPYL3
Dihydropyrimidinase-related protein 3

3

2

High-throughput

0.667

High

934838

H31
Histone H3.1

3

3

High-throughput

0.640

High

792235

MTHR
Methylenetetrahydrofolate reductase

3

0

High-throughput

0.638

High

901793

STXB1
Syntaxin-binding protein 1

3

0

High-throughput

0.638

High

917027

VISL1
Visinin-like protein 1

3

0

High-throughput

0.638

High

308769

KI20A
Kinesin-like protein KIF20A

2

2

High-throughput

0.611

High

166567

DCLK1
Serine/threonine-protein kinase DCLK1

3

1

High-throughput

0.609

High

522619

MYH7
Myosin-7

3

3

High-throughput

0.609

High

1121641

MYH4
Myosin-4

3

3

High-throughput

0.609

High

497139

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.602

High

1121598

BOREA
Borealin

1

0

Small-scale

0.586

High

1043392

CUL4B
Cullin-4B

2

0

High-throughput

0.585

High

1121638

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

0

High-throughput

0.585

High

918412

H2B1C
Histone H2B type 1-C/E/F/G/I

2

1

High-throughput

0.584

High

280114

SNPC5
snRNA-activating protein complex subunit 5

2

0

High-throughput

0.580

High

533682

GYS1
Glycogen [starch] synthase, muscle

2

0

High-throughput

0.580

High

963830

SET
Protein SET

2

0

High-throughput

0.580

High

1121602

HMBX1
Homeobox-containing protein 1

2

0

High-throughput

0.580

High

1121618

FBX17
F-box only protein 17

2

0

High-throughput

0.580

High

1121620

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1121628

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

0

High-throughput

0.580

High

1121642

EMIL1
EMILIN-1

2

3

High-throughput

0.553

High

834763

RBP2
E3 SUMO-protein ligase RanBP2

1

0

Small-scale

0.549

High

1121625

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.549

High

851382

NEK3
Serine/threonine-protein kinase Nek3

1

1

High-throughput

0.541

High

1121611

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

0

Small-scale

0.537

High

623127

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.536

High

638974

S100P
Protein S100-P

1

1

High-throughput

0.536

High

643874

SYVC
Valine--tRNA ligase

1

1

High-throughput

0.536

High

644059

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.536

High

669386

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.536

High

724857

MYH9
Myosin-9

1

3

High-throughput

0.536

High

800407

CBX5
Chromobox protein homolog 5

1

2

Small-scale

0.536

High

958696

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.536

High

1087163

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1121622

KIF2C
Kinesin-like protein KIF2C

1

1

High-throughput

0.536

High

708307

TTK
Dual specificity protein kinase TTK

1

3

Small-scale

0.520

High

1121599

SGO2
Shugoshin 2

1

0

Small-scale

0.518

High

1121600

SGO1
Shugoshin 1

1

0

Small-scale

0.518

High

1121608

MAPK5
MAP kinase-activated protein kinase 5

1

0

High-throughput

0.518

High

1121606

GA2L3
GAS2-like protein 3

1

0

Small-scale

0.513

High

932736

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.513

High

1121605

NOP9
Nucleolar protein 9

1

0

High-throughput

0.513

High

1121614

NEDD1
Protein NEDD1

1

0

High-throughput

0.513

High

1121623

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

91377

E7CU85
Baculoviral IAP repeat-containing protein 5

1

1

High-throughput

0.506

High

930248

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.504

High

1121604

H32
Histone H3.2

1

3

Small-scale

0.501

High

661281

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

828249

CENPA
Histone H3-like centromeric protein A

1

3

High-throughput

0.479

High

949802

CBX1
Chromobox protein homolog 1

1

2

High-throughput

0.479

High

952378

H33
Histone H3.3

1

3

High-throughput

0.479

High

969751

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1027029

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

1083103

DPYL2
Dihydropyrimidinase-related protein 2

1

2

High-throughput

0.479

High

1121610

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1121616

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

1121624

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

1121636

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

103887

G5E9M4
Zinc finger protein 277

1

1

High-throughput

0.470

High

278288

PIAS2
E3 SUMO-protein ligase PIAS2

1

0

Small-scale

0.460

High

148896

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

162820

XPO1
Exportin-1

1

0

Small-scale

0.458

High

179665

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

210048

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

239352

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.458

High

255842

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

433802

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

455514

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

652876

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

672846

CDC27
Cell division cycle protein 27 homolog

1

0

Small-scale

0.458

High

857477

HMGA2
High mobility group protein HMGI-C

1

0

Small-scale

0.458

High

916627

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

920211

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

922202

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

967217

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1066216

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1121612

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1121613

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

1121621

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

0

High-throughput

0.458

High

1121627

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1121630

ANLN
Anillin

1

0

High-throughput

0.458

High

1121632

DCA13
DDB1- and CUL4-associated factor 13

1

0

Small-scale

0.458

High

1121633

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1121634

RCC2
Protein RCC2

1

0

Small-scale

0.458

High

1121635

UBP35
Ubiquitin carboxyl-terminal hydrolase 35

1

0

Small-scale

0.458

High

1121639

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1121640

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1121631

ZN277
Zinc finger protein 277

1

1

High-throughput

0.439

High

320685

LDOC1
Protein LDOC1

1

0

High-throughput

0.438

High

1057493

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

Small-scale

0.426

High

594751

ATP4A
Potassium-transporting ATPase alpha chain 1

3

0

High-throughput

0.347

High

599578

SYT1
Synaptotagmin-1

2

0

High-throughput

0.328

High

1121617

TRI44
Tripartite motif-containing protein 44

2

0

High-throughput

0.328

High

237894

AP180
Clathrin coat assembly protein AP180

2

0

High-throughput

0.318

High

887111

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

2

0

High-throughput

0.318

High

1121601

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

2

0

High-throughput

0.316

High

1121603

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.316

High

1121615

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

521977

CADH1
Cadherin-1

1

0

Small-scale

0.292

High

945200

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

0

High-throughput

0.282

High

63108

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

0

High-throughput

0.279

Low

117046

KITM
Thymidine kinase 2, mitochondrial

1

0

High-throughput

0.279

Low

591345

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

1121643

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.279

Low

434211

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.249

Low

439128

SYPH
Synaptophysin

1

0

High-throughput

0.249

Low

1036387

GPM6B
Neuronal membrane glycoprotein M6-b

1

0

High-throughput

0.249

Low

1121607

CCD71
Coiled-coil domain-containing protein 71

1

0

Small-scale

0.249

Low

1121626

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1121637

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1121609

GPAM1
GPALPP motifs-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024