HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: Q0IGU7 (Q0IGU7)
HLH54F (RT01030p)
Gene: HLH54F

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9486535
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 242
+	Dm
		185785 DA_DROME (1-710): 0: 908: 100.00		O18374_DROME (1-242): 2.2e-73: 225: 99.59
+	Dm
		509356 DA_DROME (1-710): 0: 908: 100.00		MYOD_DROME (7-211): 1.74e-38: 138: 21.26
+	Dm
		509377 DA_DROME (1-710): 0: 908: 100.00		FER3_DROME (5-139): 4.92e-28: 107: 25.93
+	Dm
		509364 DA_DROME (1-710): 0: 908: 100.00		ATO_DROME (14-88): 2.9e-26: 105: 34.67
+	Dm
		509388 DA_DROME (1-710): 0: 908: 100.00		Q9W4X2_DROME (31-141): 1.71e-25: 104: 28.10
+	Dm
		509380 DA_DROME (1-710): 0: 908: 100.00		Q9VL05_DROME (23-90): 1.25e-25: 100: 39.71
+	Dm
		509390 DA_DROME (1-710): 0: 908: 100.00		AMOS_DROME (32-90): 4.18e-11: 62.1: 42.37
+	Mm
		603985 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TAL1_MOUSE (3-160): 1.33e-28: 112: 22.79
+	Mm
		1142072 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND2_MOUSE (30-95): 8.69e-26: 102: 40.91
+	Mm
		1142446 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND1_MOUSE (26-96): 1.31e-25: 101: 36.62
+	Hs
		546034 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MYOD1_HUMAN (14-209): 2.3e-33: 124: 17.48
+	Mm
		644476 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TWST1_MOUSE (23-123): 2.98e-25: 100: 28.85
+	Hs
		568226 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TAL1_HUMAN (3-160): 1.44e-30: 117: 23.42
+	Hs
		210863 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF21_HUMAN (3-131): 3.26e-28: 107: 35.04
+	Hs
		616615 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MYF6_HUMAN (2-184): 1.75e-26: 104: 17.49
+	Hs
		899129 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND2_HUMAN (30-95): 8.69e-26: 102: 40.91
+	Hs
		238594 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MUSC_HUMAN (2-129): 4.31e-25: 99.9: 35.88
+	Hs
		971805 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN1_HUMAN (31-88): 7.26e-25: 97.1: 41.38
+	Hs
		330430 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND1_HUMAN (32-95): 8.82e-17: 77.9: 39.06
+	Hs
		971838 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN2_HUMAN (34-88): 5e-11: 60.6: 41.82