HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: AMOS (Q9Y0A7)
Basic helix-loop-helix transcription factor amos (Absent MD neurons and olfactory sensilla protein) (Amos protein) (Reduced olfactory organs protein) (Rough eye protein)
Gene: AMOS

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0007423 - sensory organ development GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity and 1 others more... GO:0048663 - neuron fate commitment
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 198
+	Dm
		509356 DA_DROME (1-710): 0: 908: 100.00		MYOD_DROME (18-196): 1.44e-29: 113: 23.44
+	Dm
		509377 DA_DROME (1-710): 0: 908: 100.00		FER3_DROME (61-195): 1.1e-27: 104: 34.56
+	Dm
		509364 DA_DROME (1-710): 0: 908: 100.00		ATO_DROME (110-195): 6.59e-26: 103: 50.00
+	Dm
		80865 DA_DROME (1-710): 0: 908: 100.00		DIMM_DROME (88-194): 2.11e-24: 100: 35.51
+	Mm
		1142072 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND2_MOUSE (75-197): 7.25e-31: 113: 30.89
+	Mm
		644476 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TWST1_MOUSE (32-197): 4.51e-27: 103: 24.10
+	Mm
		1142446 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND1_MOUSE (76-197): 5.59e-26: 100: 27.05
+	Hs
		899129 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND2_HUMAN (75-197): 7.25e-31: 113: 30.89
+	Hs
		546105 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MYOG_HUMAN (56-196): 1.46e-29: 110: 24.65
+	Hs
		1271845 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		ATOH1_HUMAN (27-196): 3.39e-28: 109: 32.98
+	Hs
		616615 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MYF6_HUMAN (54-196): 3.51e-27: 104: 19.87
+	Hs
		1018388 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF15_HUMAN (70-194): 1.23e-26: 102: 25.98
+	Hs
		210863 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF21_HUMAN (90-197): 1.58e-26: 101: 27.68
+	Hs
		1039378 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		NDF1_HUMAN (129-196): 7.97e-25: 100: 47.06
+	Hs
		1261463 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TWST2_HUMAN (87-197): 2.39e-26: 100: 36.04
+	Hs
		1167653 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		ASCL4_HUMAN (75-196): 1.7e-25: 98.7: 25.41
+	Hs
		330430 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND1_HUMAN (76-197): 4.07e-25: 98.7: 25.41
+	Hs
		1076858 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TWST1_HUMAN (32-197): 1.54e-24: 96.9: 24.10
+	Hs
		568226 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TAL1_HUMAN (116-195): 8.52e-23: 95.2: 33.33
+	Hs
		1083176 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TAL2_HUMAN (138-194): 2.24e-23: 91.4: 45.61