HitPredict

Interactor 1: CDC24 (P11433)
Cell division control protein 24 (Calcium regulatory protein)
Gene: CDC24

Interactor 2: BOB1 (P38041)
Protein BOB1 (BEM1-binding protein) (Growth inhibitory protein 7)
Gene: BOI1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.888

Property	Details
Experiments	28751498, 17417630, 32327559, 20489023
Identification Methods	protein complementation assay, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PH~RhoGEF, RhoGEF~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005935 - cellular bud neck GO:0043332 - mating projection tip
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 854 Sc			1 980
+	Sc
		509426 CDC24_YEAST (1-854): 0: 591: 100.00		BOI2_YEAST (4-940): 5.86e-88: 306: 35.07
+	Mm
		57863 KALRN_MOUSE (178-775): 4.47e-69: 252: 13.43		CNKR2_MOUSE (223-890): 1.16e-56: 214: 13.56
+	Hs
		855816 VAV2_HUMAN (136-832): 4.23e-121: 388: 15.22		TITIN_HUMAN (60-720): 1.38e-11: 71.2: 6.62
+	Ce
		136804 VAV_CAEEL (139-845): 1.24e-98: 331: 14.32		UNC89_CAEEL (71-781): 3.7e-20: 99.3: 8.85
+	Hs
		203228 ITSN1_HUMAN (103-591): 3.27e-89: 312: 17.91		SYNJ1_HUMAN (441-870): 4.92e-12: 72.3: 8.76
+	Mm
		57869 KALRN_MOUSE (178-775): 4.47e-69: 252: 13.43		ANK2_MOUSE (312-745): 4.64e-09: 62.8: 12.47