Protein: ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338)

Gene: ABCG2
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q9UNQ0

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0008514 - organic anion transmembrane transporter activity
GO:0008559 - ABC-type xenobiotic transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1462377

ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2

6

13

Small-scale

0.934

High

541067

PIM1
Serine/threonine-protein kinase pim-1

1

1

Small-scale

0.700

High

157990

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.618

High

1387028

HAVR1
Hepatitis A virus cellular receptor 1

1

0

Small-scale

0.586

High

648322

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

0

Small-scale

0.554

High

1414946

RN126
E3 ubiquitin-protein ligase RNF126

1

0

Small-scale

0.537

High

64964

ARRD5
Arrestin domain-containing protein 5

1

1

High-throughput

0.536

High

178861

SCAM1
Secretory carrier-associated membrane protein 1

1

1

High-throughput

0.536

High

901680

RAB7A
Ras-related protein Rab-7a

1

2

High-throughput

0.536

High

239896

PCDH7
Protocadherin-7

1

0

High-throughput

0.513

High

444021

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

0

High-throughput

0.513

High

609842

LEG3
Galectin-3

1

0

High-throughput

0.513

High

856987

BAG6
Large proline-rich protein BAG6

1

0

Small-scale

0.513

High

1325468

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

1447569

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.513

High

178444

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.479

High

331419

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

462047

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.479

High

508836

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

Small-scale

0.479

High

543304

UBL4A
Ubiquitin-like protein 4A

1

6

Small-scale

0.479

High

679288

DNJB1
DnaJ homolog subfamily B member 1

1

1

Small-scale

0.479

High

1035992

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1280602

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

Small-scale

0.479

High

1385918

CHM4C
Charged multivesicular body protein 4c

1

10

High-throughput

0.479

High

1433126

CHM4B
Charged multivesicular body protein 4b

1

10

High-throughput

0.479

High

1462267

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

Small-scale

0.479

High

415936

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.458

High

466716

GLI1
Zinc finger protein GLI1

1

0

Small-scale

0.458

High

538121

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.458

High

935293

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

1114657

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1141041

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1272445

GET4
Golgi to ER traffic protein 4 homolog

1

0

Small-scale

0.458

High

1401063

PHF12
PHD finger protein 12

1

0

High-throughput

0.458

High

1436556

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1447441

ANLN
Anillin

1

0

High-throughput

0.458

High

211193

CTR4
Cationic amino acid transporter 4

1

6

High-throughput

0.445

High

912728

CTR2
Cationic amino acid transporter 2

1

6

High-throughput

0.445

High

1458327

RHCG
Ammonium transporter Rh type C

1

3

High-throughput

0.445

High

337153

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

1408089

SC6A7
Sodium-dependent proline transporter

1

0

High-throughput

0.426

High

258354

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.279

Low

1160799

DREB
Drebrin

1

0

High-throughput

0.279

Low

1162618

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.279

Low

1462378

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025