HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: OSH1 (P35845)
Oxysterol-binding protein homolog 1 (Oxysterol-binding protein-related protein 1) (ORP 1) (OSBP-related protein 1)
Gene: SWH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	22940862, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 1188
+	Sc
		728873 SSB2_YEAST (1-613): 0: 1118: 99.35		OSH1_YEAST (1-1188): 0: 911: 100.00
+	Sc
		513292 SSB1_YEAST (1-613): 0: 1128: 100.00		OSH2_YEAST (1-1188): 0: 787: 46.94
+	Sc
		769860 SSB2_YEAST (1-613): 0: 1118: 99.35		OSH2_YEAST (1-1188): 0: 787: 46.94
+	Sc
		511181 SSB1_YEAST (1-613): 0: 1128: 100.00		OSH3_YEAST (288-1188): 1.32e-120: 399: 18.47
+	Sc
		511203 SSB1_YEAST (1-613): 0: 1128: 100.00		OSH7_YEAST (754-1169): 1.34e-113: 362: 21.85
+	Sc
		512393 SSB1_YEAST (1-613): 0: 1128: 100.00		OSH6_YEAST (794-1172): 1.79e-110: 355: 23.70
+	Sc
		753721 SSB2_YEAST (1-613): 0: 1118: 99.35		OSH7_YEAST (754-1169): 1.34e-113: 362: 21.85
+	Sc
		769222 SSB2_YEAST (1-613): 0: 1118: 99.35		OSH6_YEAST (794-1172): 1.79e-110: 355: 23.70
+	Sc
		450246 HSP73_YEAST (9-611): 0: 677: 60.66		OSH2_YEAST (1-1188): 0: 787: 46.94
+	Hs
		504708 HSP7C_HUMAN (5-612): 0: 900: 59.84		OSBL7_HUMAN (238-1183): 1.15e-168: 522: 19.96
+	Sc
		510863 SSB1_YEAST (1-613): 0: 1128: 100.00		KES1_YEAST (792-1165): 1.27e-80: 273: 18.60
+	Sc
		728849 SSB2_YEAST (1-613): 0: 1118: 99.35		KES1_YEAST (792-1165): 1.27e-80: 273: 18.60
+	Hs
		504689 HSP7C_HUMAN (5-612): 0: 900: 59.84		OSB10_HUMAN (287-659): 2.35e-20: 99.4: 14.44
+	Hs
		871765 HSP72_HUMAN (4-612): 0: 891: 59.97		OSB11_HUMAN (274-659): 2.37e-21: 102: 13.01