Protein: GEMI2
Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1)

Gene: GEMI2, GEMIN2
Organism: Homo sapiens
Interactions: 107
UniProt ID: O14893

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000387 - spliceosomal snRNP assembly
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

157740

SMN
Survival motor neuron protein

19

2

Small-scale

0.989

High

157724

RUXF
Small nuclear ribonucleoprotein F

7

4

Small-scale

0.965

High

157730

RSMN
Small nuclear ribonucleoprotein-associated protein N

3

1

Small-scale

0.866

High

157727

SMD1
Small nuclear ribonucleoprotein Sm D1

3

3

Small-scale

0.855

High

157723

RUXE
Small nuclear ribonucleoprotein E

4

0

Small-scale

0.846

High

157725

RUXG
Small nuclear ribonucleoprotein G

3

8

Small-scale

0.839

High

157705

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

1

High-throughput

0.811

High

157726

LSM6
U6 snRNA-associated Sm-like protein LSm6

2

4

High-throughput

0.811

High

157728

SMD2
Small nuclear ribonucleoprotein Sm D2

3

0

Small-scale

0.796

High

157781

DDX20
Probable ATP-dependent RNA helicase DDX20

8

1

Small-scale

0.750

High

157783

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

8

High-throughput

0.691

High

157772

GEMI7
Gem-associated protein 7

5

0

Small-scale

0.688

High

157699

RU17
U1 small nuclear ribonucleoprotein 70 kDa

5

0

Small-scale

0.685

High

157756

GEMI6
Gem-associated protein 6

5

0

Small-scale

0.684

High

157775

GEMI8
Gem-associated protein 8

5

0

Small-scale

0.684

High

157720

GEMI4
Gem-associated protein 4

4

0

Small-scale

0.664

High

157787

STRAP
Serine-threonine kinase receptor-associated protein

4

0

Small-scale

0.664

High

157778

SPN90
NCK-interacting protein with SH3 domain

3

0

High-throughput

0.646

High

157729

ACTA
Actin, aortic smooth muscle

2

1

High-throughput

0.628

High

157755

GEMI5
Gem-associated protein 5

3

0

Small-scale

0.628

High

157690

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

5

High-throughput

0.618

High

157786

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

4

High-throughput

0.618

High

157709

HXD10
Homeobox protein Hox-D10

2

1

High-throughput

0.606

High

157718

MEOX1
Homeobox protein MOX-1

2

1

High-throughput

0.606

High

157750

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.585

High

157692

IMA7
Importin subunit alpha-7

2

0

High-throughput

0.580

High

157694

RPP14
Ribonuclease P protein subunit p14

2

0

High-throughput

0.580

High

157706

PSB1
Proteasome subunit beta type-1

2

0

High-throughput

0.580

High

157708

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

157735

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

157777

SPG21
Maspardin

2

0

High-throughput

0.580

High

68381

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

8

High-throughput

0.575

High

157774

STRN4
Striatin-4

2

1

High-throughput

0.574

High

157696

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

157789

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.537

High

157701

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

157712

FUS
RNA-binding protein FUS

1

1

High-throughput

0.536

High

157741

P3H1
Prolyl 3-hydroxylase 1

1

1

High-throughput

0.536

High

157763

HDA11
Histone deacetylase 11

1

1

High-throughput

0.536

High

157759

RAD50
DNA repair protein RAD50

1

0

Small-scale

0.529

High

64470

GOG8A
Golgin subfamily A member 8A

1

0

High-throughput

0.513

High

157700

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

157703

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

157717

CLK3
Dual specificity protein kinase CLK3

1

0

High-throughput

0.513

High

157732

BAX
Apoptosis regulator BAX

1

0

High-throughput

0.513

High

157734

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.513

High

157738

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

157748

FAM9B
Protein FAM9B

1

0

High-throughput

0.513

High

157749

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

157760

FGF14
Fibroblast growth factor 14

1

0

High-throughput

0.513

High

157765

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

0

High-throughput

0.513

High

157766

ERMAP
Erythroid membrane-associated protein

1

0

High-throughput

0.513

High

157780

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

0

High-throughput

0.513

High

157702

LEG1
Galectin-1

1

0

Small-scale

0.493

High

157739

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.493

High

157693

CRTAP
Cartilage-associated protein

1

1

High-throughput

0.489

High

157742

ACTBL
Beta-actin-like protein 2

1

1

High-throughput

0.489

High

157782

NUFP1
FMR1-interacting protein NUFIP1

1

0

Small-scale

0.480

High

157788

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

157758

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

157688

GEMI2
Gem-associated protein 2

1

0

High-throughput

0.460

High

122363

MEN1
Menin

1

0

High-throughput

0.458

High

155196

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

157689

XPO1
Exportin-1

1

0

High-throughput

0.458

High

157691

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

157695

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

157697

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

157707

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

Small-scale

0.458

High

157711

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.458

High

157713

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

157716

SRP09
Signal recognition particle 9 kDa protein

1

0

Small-scale

0.458

High

157719

COPA
Coatomer subunit alpha

1

0

Small-scale

0.458

High

157721

SRP54
Signal recognition particle subunit SRP54

1

0

Small-scale

0.458

High

157722

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

157731

VIGLN
Vigilin

1

0

High-throughput

0.458

High

157733

DHX9
ATP-dependent RNA helicase A

1

0

Small-scale

0.458

High

157737

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

157746

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

157754

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

157757

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

157761

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

Small-scale

0.458

High

157762

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

157764

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

157767

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

157768

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

157769

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

157771

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

157773

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.458

High

157776

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

Small-scale

0.458

High

157785

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.458

High

157744

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

157770

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

157784

AGO1
Protein argonaute-1

1

0

High-throughput

0.426

High

157747

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

0

High-throughput

0.347

High

157698

ACM4
Muscarinic acetylcholine receptor M4

2

0

High-throughput

0.328

High

157752

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

157751

BEND7
BEN domain-containing protein 7

2

0

High-throughput

0.316

High

157704

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.279

Low

157714

GLR
Glucagon receptor

1

0

High-throughput

0.279

Low

157736

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

157743

FAXC
Failed axon connections homolog

1

0

High-throughput

0.279

Low

157753

CERK1
Ceramide kinase

1

0

High-throughput

0.279

Low

157779

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

157715

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.265

Low

157710

PROF2
Profilin-2

1

0

High-throughput

0.249

Low

157745

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024