Protein: AFG2B
ATPase family gene 2 protein homolog B (EC 3.6.4.10) (AFG2 AAA ATPase homolog B) (Ribosome biogenesis protein SPATA5L1) (Spermatogenesis-associated protein 5-like protein 1)

Gene: AFG2B
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q9BVQ7

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005819 - spindle
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1333194

AFG2A
ATPase family gene 2 protein homolog A

4

17

High-throughput

0.892

High

1415593

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

3

9

High-throughput

0.847

High

1279507

CMKMT
Calmodulin-lysine N-methyltransferase

2

4

High-throughput

0.789

High

944063

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

2

9

High-throughput

0.712

High

675141

TNR6
Tumor necrosis factor receptor superfamily member 6

3

4

High-throughput

0.667

High

1361476

IFT81
Intraflagellar transport protein 81 homolog

3

9

High-throughput

0.667

High

1415590

CINP
Cyclin-dependent kinase 2-interacting protein

3

1

High-throughput

0.662

High

1415602

AIRIM
AFG2-interacting ribosome maturation factor

3

1

High-throughput

0.662

High

537825

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.628

High

1415606

FMN2
Formin-2

2

3

High-throughput

0.628

High

174601

TRI66
Tripartite motif-containing protein 66

1

9

High-throughput

0.618

High

342308

BRD1
Bromodomain-containing protein 1

1

7

High-throughput

0.618

High

1415599

BRD7
Bromodomain-containing protein 7

1

10

High-throughput

0.618

High

1114182

CUL3
Cullin-3

2

12

High-throughput

0.611

High

1295031

TMM25
Transmembrane protein 25

3

2

High-throughput

0.609

High

1406561

METH
Methionine synthase

2

0

High-throughput

0.602

High

606032

CAN2
Calpain-2 catalytic subunit

2

2

High-throughput

0.601

High

920253

PLK1
Serine/threonine-protein kinase PLK1

2

11

High-throughput

0.584

High

610459

PRS6A
26S proteasome regulatory subunit 6A

1

20

High-throughput

0.575

High

1403216

Q96T11
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.575

High

1415611

DKKL1
Dickkopf-like protein 1

2

3

High-throughput

0.574

High

1227379

A16L1
Autophagy-related protein 16-1

2

10

High-throughput

0.571

High

1415614

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.553

High

1415618

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

2

2

High-throughput

0.549

High

64904

RCCD1
RCC1 domain-containing protein 1

1

7

High-throughput

0.536

High

286784

SKAP2
Src kinase-associated phosphoprotein 2

1

6

High-throughput

0.536

High

315967

RECQ4
ATP-dependent DNA helicase Q4

1

11

High-throughput

0.536

High

549672

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

4

High-throughput

0.536

High

686391

RL13
Large ribosomal subunit protein eL13

1

6

High-throughput

0.536

High

693947

RL10
Large ribosomal subunit protein uL16

1

4

High-throughput

0.536

High

849239

KSYK
Tyrosine-protein kinase SYK

1

3

High-throughput

0.536

High

898134

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

7

High-throughput

0.536

High

960866

RL15
Large ribosomal subunit protein eL15

1

3

High-throughput

0.536

High

1111239

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.536

High

1148028

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.536

High

1153220

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

6

High-throughput

0.536

High

1272838

DHX32
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

1

1

High-throughput

0.536

High

1287882

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

2

High-throughput

0.536

High

1381271

FBXW5
F-box/WD repeat-containing protein 5

1

1

High-throughput

0.536

High

1414644

TCAB1
Telomerase Cajal body protein 1

1

7

High-throughput

0.536

High

1415594

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

1

High-throughput

0.536

High

1415596

IF122
Intraflagellar transport protein 122 homolog

1

7

High-throughput

0.536

High

1415597

WDR6
tRNA

1

15

High-throughput

0.536

High

1415598

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.536

High

1415608

KLH14
Kelch-like protein 14

1

3

High-throughput

0.536

High

1415609

WRP73
WD repeat-containing protein WRAP73

1

9

High-throughput

0.536

High

1415615

CLC11
C-type lectin domain family 11 member A

1

2

High-throughput

0.536

High

220010

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

1310371

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1410072

USB1
U6 snRNA phosphodiesterase 1

1

0

High-throughput

0.513

High

1413860

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.513

High

1415601

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.513

High

1415605

SPHK1
Sphingosine kinase 1

1

0

High-throughput

0.513

High

1415613

PALD
Paladin

1

0

High-throughput

0.513

High

964444

SUMO2
Small ubiquitin-related modifier 2

1

8

High-throughput

0.501

High

238742

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

2

High-throughput

0.489

High

261549

B4GT2
Beta-1,4-galactosyltransferase 2

1

1

High-throughput

0.489

High

1042063

LMNB2
Lamin-B2

1

11

High-throughput

0.489

High

1085701

TBL3
Transducin beta-like protein 3

1

13

High-throughput

0.489

High

1292765

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

4

High-throughput

0.489

High

1349104

F174A
Membrane protein FAM174A

1

3

High-throughput

0.489

High

1392607

TIMD4
T-cell immunoglobulin and mucin domain-containing protein 4

1

1

High-throughput

0.489

High

1415619

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

1415620

EMIL1
EMILIN-1

1

4

High-throughput

0.489

High

173301

XPO1
Exportin-1

1

11

High-throughput

0.479

High

194327

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

294277

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

331281

KI20A
Kinesin-like protein KIF20A

1

15

High-throughput

0.479

High

412544

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

473039

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

5

High-throughput

0.479

High

831357

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

861275

MAP1B
Microtubule-associated protein 1B

1

6

High-throughput

0.479

High

980258

H4
Histone H4

1

3

High-throughput

0.479

High

1108105

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

1138587

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

1140786

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

1178354

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1255354

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1329846

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1339686

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1352186

SSH3
Protein phosphatase Slingshot homolog 3

1

4

High-throughput

0.479

High

1364570

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

1393656

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

1411270

LZTS2
Leucine zipper putative tumor suppressor 2

1

15

High-throughput

0.479

High

1415600

ANLN
Anillin

1

3

High-throughput

0.479

High

1415607

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

1415610

ANC2
Anaphase-promoting complex subunit 2

1

12

High-throughput

0.479

High

1415612

FBW1B
F-box/WD repeat-containing protein 11

1

12

High-throughput

0.479

High

1383398

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

1093170

STK4
Serine/threonine-protein kinase 4

1

8

High-throughput

0.457

High

430314

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

1226256

CP135
Centrosomal protein of 135 kDa

1

6

High-throughput

0.445

High

1415603

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.445

High

106582

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

1215804

RC3H1
Roquin-1

1

2

High-throughput

0.437

High

1243086

CF161
Cilia- and flagella-associated protein 161

1

1

High-throughput

0.437

High

1249180

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1415595

RC3H2
Roquin-2

1

4

High-throughput

0.437

High

1415604

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

2

High-throughput

0.437

High

239192

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.426

High

338180

NSA2
Ribosome biogenesis protein NSA2 homolog

1

2

High-throughput

0.407

High

1253654

PKHG7
Pleckstrin homology domain-containing family G member 7

1

3

High-throughput

0.407

High

1415616

S27A6
Long-chain fatty acid transport protein 6

1

4

High-throughput

0.407

High

1415617

TIM8B
Mitochondrial import inner membrane translocase subunit Tim8 B

1

2

High-throughput

0.407

High

1415591

RM04
Large ribosomal subunit protein uL4m

3

0

High-throughput

0.347

High

878085

AGRE5
Adhesion G protein-coupled receptor E5

1

0

High-throughput

0.279

Low

1017807

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

1415592

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025