Protein: AFG2A
ATPase family gene 2 protein homolog A (EC 3.6.4.10) (AFG2 AAA ATPase homolog A) (Ribosome biogenesis protein SPATA5) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5)

Gene: AFG2A
Organism: Homo sapiens
Interactions: 105
UniProt ID: Q8NB90

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005819 - spindle
GO:0005829 - cytosol
GO:0007283 - spermatogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1333194

AFG2B
ATPase family gene 2 protein homolog B

4

17

High-throughput

0.892

High

242296

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.754

High

851371

PRS6B
26S proteasome regulatory subunit 6B

1

14

High-throughput

0.691

High

968994

PRS8
26S proteasome regulatory subunit 8

1

18

High-throughput

0.691

High

1333195

CINP
Cyclin-dependent kinase 2-interacting protein

4

1

High-throughput

0.691

High

1333209

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.631

High

700686

PSA5
Proteasome subunit alpha type-5

1

9

Small-scale

0.618

High

1333176

AFG2A
ATPase family gene 2 protein homolog A

1

17

High-throughput

0.618

High

1333197

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.618

High

1333199

BRD7
Bromodomain-containing protein 7

1

10

High-throughput

0.618

High

1333203

ATD3A
ATPase family AAA domain-containing protein 3A

1

18

High-throughput

0.618

High

675084

TNR6
Tumor necrosis factor receptor superfamily member 6

2

4

High-throughput

0.611

High

920120

PLK1
Serine/threonine-protein kinase PLK1

2

11

High-throughput

0.584

High

943993

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.575

High

1333210

DKKL1
Dickkopf-like protein 1

2

3

High-throughput

0.574

High

396527

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

1226181

CP135
Centrosomal protein of 135 kDa

2

6

High-throughput

0.571

High

1227070

A16L1
Autophagy-related protein 16-1

2

10

High-throughput

0.571

High

174561

TRI66
Tripartite motif-containing protein 66

1

9

High-throughput

0.553

High

342259

BRD1
Bromodomain-containing protein 1

1

7

High-throughput

0.553

High

1333212

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.553

High

1333178

F174A
Membrane protein FAM174A

2

3

High-throughput

0.549

High

138224

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

6

High-throughput

0.536

High

173087

XPO1
Exportin-1

1

11

High-throughput

0.536

High

564067

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.536

High

686278

RL13
Large ribosomal subunit protein eL13

1

6

High-throughput

0.536

High

686840

S10A4
Protein S100-A4

1

4

High-throughput

0.536

High

849207

KSYK
Tyrosine-protein kinase SYK

1

3

High-throughput

0.536

High

960803

RL15
Large ribosomal subunit protein eL15

1

3

High-throughput

0.536

High

981590

RAN
GTP-binding nuclear protein Ran

1

10

High-throughput

0.536

High

1152156

MARE1
Microtubule-associated protein RP/EB family member 1

1

4

High-throughput

0.536

High

1325984

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.536

High

1333191

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

439788

INSR
Insulin receptor

1

4

High-throughput

0.500

High

133280

P2Y10
Putative P2Y purinoceptor 10

1

2

High-throughput

0.489

High

847785

SSRB
Translocon-associated protein subunit beta

1

1

High-throughput

0.489

High

1111114

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.489

High

1295011

TMM25
Transmembrane protein 25

1

2

High-throughput

0.489

High

1333186

TIMD4
T-cell immunoglobulin and mucin domain-containing protein 4

1

1

High-throughput

0.489

High

1333216

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

3

High-throughput

0.489

High

1333219

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

129260

MEN1
Menin

1

2

High-throughput

0.479

High

157621

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.479

High

319909

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

324987

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

348615

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

5

High-throughput

0.479

High

372595

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

412262

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

445969

ENOA
Alpha-enolase

1

4

High-throughput

0.479

High

537529

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

637638

FLNA
Filamin-A

1

7

High-throughput

0.479

High

659260

SP100
Nuclear autoantigen Sp-100

1

4

High-throughput

0.479

High

791541

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

799302

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.479

High

831072

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

1113718

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1115822

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.479

High

1138403

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

1161548

IF16
Gamma-interferon-inducible protein 16

1

4

High-throughput

0.479

High

1178255

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1254663

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1325362

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.479

High

1333177

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1333179

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1333181

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

1333184

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

1333185

AURKB
Aurora kinase B

1

6

High-throughput

0.479

High

1333187

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

1333189

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1333192

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.479

High

1333196

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

6

High-throughput

0.479

High

1333198

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1333200

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1333201

ANLN
Anillin

1

3

High-throughput

0.479

High

1333205

AIRIM
AFG2-interacting ribosome maturation factor

1

1

High-throughput

0.479

High

1333207

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

1333208

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.479

High

1333211

FBW1B
F-box/WD repeat-containing protein 11

1

12

High-throughput

0.479

High

1333215

FBW1A
F-box/WD repeat-containing protein 1A

1

12

High-throughput

0.479

High

1333206

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

964373

SUMO2
Small ubiquitin-related modifier 2

1

8

High-throughput

0.457

High

1333190

TCPQM
T-complex protein 1 subunit theta-like 2

1

12

High-throughput

0.445

High

1333214

CLC11
C-type lectin domain family 11 member A

1

2

High-throughput

0.445

High

106286

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

194268

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.437

High

472897

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

5

High-throughput

0.437

High

979998

H4
Histone H4

1

3

High-throughput

0.437

High

1125007

RCN2
Reticulocalbin-2

1

4

High-throughput

0.437

High

1126126

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1243082

CF161
Cilia- and flagella-associated protein 161

1

1

High-throughput

0.437

High

1329748

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.437

High

1333180

DNS2B
Deoxyribonuclease-2-beta

1

1

High-throughput

0.437

High

1333188

RCC1L
RCC1-like G exchanging factor-like protein

1

4

High-throughput

0.437

High

1333193

ZFY21
Zinc finger FYVE domain-containing protein 21

1

2

Small-scale

0.437

High

1333204

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

5

Small-scale

0.437

High

1187341

DC4L1
DDB1- and CUL4-associated factor 4-like protein 1

1

0

High-throughput

0.426

High

338156

NSA2
Ribosome biogenesis protein NSA2 homolog

1

2

High-throughput

0.407

High

1165388

Q17RG0
Autophagy-related protein 16-1

1

12

High-throughput

0.407

High

1333182

ESR2
Estrogen receptor beta

1

10

High-throughput

0.407

High

1333183

PIGT
GPI-anchor transamidase component PIGT

1

1

High-throughput

0.407

High

1333202

S39A9
Zinc transporter ZIP9

1

1

High-throughput

0.407

High

1333217

S27A6
Long-chain fatty acid transport protein 6

1

4

High-throughput

0.407

High

1333218

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

Small-scale

0.249

Low

1333213

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025