HitPredict

Interactor 1: TPC2A (P0DI81)
Trafficking protein particle complex subunit 2 (Sedlin)
Gene: TRAPPC2

Interactor 2: REPS1 (Q96D71)
RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)
Gene: REPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23414517
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 796
+	Hs
		515723 TPC2B_HUMAN (1-140): 8.83e-67: 200: 100.00		REPS1_HUMAN (1-796): 8.79e-115: 368: 100.00
+	Hs
		1387121 TPC2L_HUMAN (4-133): 2.82e-41: 135: 20.42		REPS1_HUMAN (1-796): 8.79e-115: 368: 100.00
+	Hs
		515658 TPC2A_HUMAN (1-140): 8.83e-67: 200: 100.00		EP15R_HUMAN (8-735): 4.6e-75: 263: 13.93
+	Hs
		515739 TPC2B_HUMAN (1-140): 8.83e-67: 200: 100.00		EP15R_HUMAN (8-735): 4.6e-75: 263: 13.93
+	Hs
		1339267 TPC2L_HUMAN (4-133): 2.82e-41: 135: 20.42		REPS2_HUMAN (4-796): 7.4e-45: 173: 31.53