Protein: REPS1
RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)

Gene: REPS1
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q96D71

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1145908

RBP1
RalA-binding protein 1

11

10

Small-scale

0.758

High

1386659

AP2M1
AP-2 complex subunit mu

5

17

High-throughput

0.718

High

1387114

BMP2K
BMP-2-inducible protein kinase

5

18

High-throughput

0.712

High

1178784

AAK1
AP2-associated protein kinase 1

4

15

High-throughput

0.691

High

989076

AP2B1
AP-2 complex subunit beta

3

20

High-throughput

0.667

High

922602

AP2S1
AP-2 complex subunit sigma

3

20

High-throughput

0.662

High

1339261

REPS2
RalBP1-associated Eps domain-containing protein 2

3

18

High-throughput

0.662

High

1360367

STON2
Stonin-2

1

17

Small-scale

0.647

High

1387121

TPC2L
Trafficking protein particle complex subunit 2-like protein

2

5

High-throughput

0.644

High

1387106

SGF29
SAGA-associated factor 29

3

0

High-throughput

0.638

High

271735

HIP1R
Huntingtin-interacting protein 1-related protein

2

4

High-throughput

0.628

High

286706

STX11
Syntaxin-11

2

4

High-throughput

0.628

High

1129851

EPN4
Clathrin interactor 1

2

20

High-throughput

0.628

High

1202490

RUN3A
RUN domain-containing protein 3A

2

5

High-throughput

0.628

High

1293280

LSR
Lipolysis-stimulated lipoprotein receptor

2

3

High-throughput

0.628

High

1336432

PNMA1
Paraneoplastic antigen Ma1

2

2

High-throughput

0.628

High

1387108

STALP
AMSH-like protease

2

2

High-throughput

0.628

High

1387123

MYO6
Unconventional myosin-VI

2

7

High-throughput

0.628

High

1154151

ITSN1
Intersectin-1

2

19

Small-scale

0.614

High

1328439

S2541
Mitochondrial carrier protein SCaMC-3L

3

1

High-throughput

0.609

High

1387122

PNMA2
Paraneoplastic antigen Ma2

3

2

High-throughput

0.604

High

323766

AP2A2
AP-2 complex subunit alpha-2

2

20

High-throughput

0.601

High

344766

AP2A1
AP-2 complex subunit alpha-1

2

20

High-throughput

0.601

High

1145318

RNPS1
RNA-binding protein with serine-rich domain 1

2

4

High-throughput

0.601

High

396681

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

1125381

FLNC
Filamin-C

1

8

High-throughput

0.541

High

1146282

ANKR1
Ankyrin repeat domain-containing protein 1

1

19

High-throughput

0.541

High

239604

MED14
Mediator of RNA polymerase II transcription subunit 14

1

3

High-throughput

0.536

High

269970

AUXI
Auxilin

1

4

High-throughput

0.536

High

340660

STABP
STAM-binding protein

1

2

High-throughput

0.536

High

358774

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.536

High

451046

LDHB
L-lactate dehydrogenase B chain

1

1

High-throughput

0.536

High

483184

CLCA
Clathrin light chain A

1

10

High-throughput

0.536

High

564189

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.536

High

889322

NUMB
Protein numb homolog

1

20

Small-scale

0.536

High

1022191

DAB2
Disabled homolog 2

1

20

High-throughput

0.536

High

1026171

CLH1
Clathrin heavy chain 1

1

8

High-throughput

0.536

High

1083292

AP1B1
AP-1 complex subunit beta-1

1

20

High-throughput

0.536

High

1115892

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

13

High-throughput

0.536

High

1121969

ARHG7
Rho guanine nucleotide exchange factor 7

1

17

High-throughput

0.536

High

1152191

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.536

High

1315633

ENTD1
ENTH domain-containing protein 1

1

20

High-throughput

0.536

High

1387107

TRI11
E3 ubiquitin-protein ligase TRIM11

1

4

High-throughput

0.536

High

1387110

WNK3
Serine/threonine-protein kinase WNK3

1

4

High-throughput

0.536

High

1387116

GTSE1
G2 and S phase-expressed protein 1

1

2

High-throughput

0.536

High

1387127

MB212
Protein mab-21-like 2

1

2

High-throughput

0.536

High

1065853

MZT1
Mitotic-spindle organizing protein 1

1

0

High-throughput

0.518

High

49000

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.513

High

570950

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

867334

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

1387112

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

1387115

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.513

High

1387126

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.513

High

728375

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.501

High

1109351

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

High-throughput

0.501

High

515723

TPC2B
Trafficking protein particle complex subunit 2B

1

5

High-throughput

0.481

High

1230929

WWC2
Protein WWC2

1

6

High-throughput

0.481

High

1387105

REPS1
RalBP1-associated Eps domain-containing protein 1

1

17

High-throughput

0.481

High

1387118

ITSN2
Intersectin-2

1

18

High-throughput

0.481

High

242542

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

362344

ABL1
Tyrosine-protein kinase ABL1

1

9

High-throughput

0.479

High

401276

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

412415

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

541631

FGFR1
Fibroblast growth factor receptor 1

1

17

High-throughput

0.479

High

582917

EZRI
Ezrin

1

6

High-throughput

0.479

High

589374

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

625837

RXRA
Retinoic acid receptor RXR-alpha

1

5

High-throughput

0.479

High

643020

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

4

High-throughput

0.479

High

683499

IKBA
NF-kappa-B inhibitor alpha

1

17

Small-scale

0.479

High

714339

PML
Protein PML

1

7

High-throughput

0.479

High

715719

MARCS
Myristoylated alanine-rich C-kinase substrate

1

6

High-throughput

0.479

High

831218

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

862360

YAP1
Transcriptional coactivator YAP1

1

10

High-throughput

0.479

High

870153

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

1

High-throughput

0.479

High

883061

AMPH
Amphiphysin

1

10

Small-scale

0.479

High

896607

VASP
Vasodilator-stimulated phosphoprotein

1

4

High-throughput

0.479

High

986622

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.479

High

1024750

VIGLN
Vigilin

1

2

High-throughput

0.479

High

1245259

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

1

High-throughput

0.479

High

1254998

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

1272876

RFIP2
Rab11 family-interacting protein 2

1

8

Small-scale

0.479

High

1280404

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

6

High-throughput

0.479

High

1289529

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1324908

RHG18
Rho GTPase-activating protein 18

1

6

High-throughput

0.479

High

1387109

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

14

Small-scale

0.479

High

1387117

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1387120

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1387124

RHG26
Rho GTPase-activating protein 26

1

3

High-throughput

0.479

High

1387125

RNF6
E3 ubiquitin-protein ligase RNF6

1

3

High-throughput

0.479

High

617237

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

0

High-throughput

0.460

High

1135772

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1252928

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1348175

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

515649

TPC2A
Trafficking protein particle complex subunit 2

1

5

High-throughput

0.457

High

1387113

CASS4
Cas scaffolding protein family member 4

1

7

High-throughput

0.457

High

72389

A9UF07
Tyrosine-protein kinase ABL1

1

10

High-throughput

0.445

High

255159

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

1209495

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

1234902

PKHA7
Pleckstrin homology domain-containing family A member 7

1

14

High-throughput

0.445

High

1387111

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

106434

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

1276622

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

1098582

GPS2
G protein pathway suppressor 2

1

0

High-throughput

0.426

High

1214171

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.426

High

1167097

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

1

High-throughput

0.407

High

553037

PIP
Prolactin-inducible protein

2

0

High-throughput

0.313

High

694382

CO8A1
Collagen alpha-1(VIII) chain

1

0

High-throughput

0.279

Low

1307238

TF2LY
Homeobox protein TGIF2LY

1

0

High-throughput

0.279

Low

1387119

COMD3
COMM domain-containing protein 3

1

0

High-throughput

0.279

Low

361711

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025