Interactor 1: PRPS2 (P11908)
Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II)
Gene: PRPS2
Interactor 2: KPRA (Q14558)
Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39)
Gene: PRPSAP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.969 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 26186194, 28514442, 32296183, 33961781, 9366267, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pribosyl_synth~Pribosyl_synth, Pribosyl_synth~Pribosyltran_N, Pribosyltran_N~Pribosyltran_N |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0002189 - ribose phosphate diphosphokinase complex GO:0004749 - ribose phosphate diphosphokinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm and 3 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
