HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 20096703, 17785442
Identification Methods x-ray crystallography, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PABP~PABP, RRM_1~RRM_1
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003730 - mRNA 3'-UTR binding
and 25 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 636
Hs

1 636
+ Hs
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+ Mm
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+ Zm
+ Sc
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024