Protein: APC10
Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10)

Gene: APC10, ANAPC10
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q9UM13

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

718662

CDC27
Cell division cycle protein 27 homolog

11

15

Small-scale

0.973

High

1460728

CDC23
Cell division cycle protein 23 homolog

3

17

High-throughput

0.855

High

1460777

ANC2
Anaphase-promoting complex subunit 2

2

9

Small-scale

0.789

High

1460768

APC4
Anaphase-promoting complex subunit 4

8

3

Small-scale

0.745

High

1086937

CDC20
Cell division cycle protein 20 homolog

6

10

Small-scale

0.717

High

1093087

CDC16
Cell division cycle protein 16 homolog

4

17

Small-scale

0.691

High

948612

APC15
Anaphase-promoting complex subunit 15

3

0

Small-scale

0.638

High

1340925

CDC26
Anaphase-promoting complex subunit CDC26

3

0

High-throughput

0.634

High

1387385

APC16
Anaphase-promoting complex subunit 16

3

0

High-throughput

0.634

High

1461215

FBX5
F-box only protein 5

2

3

Small-scale

0.619

High

1412133

APC13
Anaphase-promoting complex subunit 13

2

0

High-throughput

0.602

High

1460759

APC5
Anaphase-promoting complex subunit 5

2

3

High-throughput

0.601

High

1452598

APC11
Anaphase-promoting complex subunit 11

2

5

Small-scale

0.595

High

1461893

FZR1
Fizzy-related protein homolog

2

10

Small-scale

0.563

High

1014656

SMAD3
Mothers against decapentaplegic homolog 3

1

3

Small-scale

0.561

High

1153944

SMAD2
Mothers against decapentaplegic homolog 2

1

3

Small-scale

0.561

High

718046

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

5

Small-scale

0.536

High

1163287

H2B2E
Histone H2B type 2-E

1

3

High-throughput

0.536

High

1399407

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

0

Small-scale

0.529

High

951901

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.501

High

692837

CALL3
Calmodulin-like protein 3

1

3

High-throughput

0.489

High

1060934

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

3

Small-scale

0.481

High

173549

XPO1
Exportin-1

1

4

High-throughput

0.479

High

243281

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

251825

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

5

Small-scale

0.479

High

316154

RECQ4
ATP-dependent DNA helicase Q4

1

13

High-throughput

0.479

High

322347

GLSK
Glutaminase kidney isoform, mitochondrial

1

3

Small-scale

0.479

High

573910

CCNB1
G2/mitotic-specific cyclin-B1

1

1

Small-scale

0.479

High

712901

CASP1
Caspase-1

1

2

Small-scale

0.479

High

771618

HXD13
Homeobox protein Hox-D13

1

1

Small-scale

0.479

High

908875

NEK2
Serine/threonine-protein kinase Nek2

1

5

High-throughput

0.479

High

916064

NUP98
Nuclear pore complex protein Nup98-Nup96

1

4

Small-scale

0.479

High

980536

H4
Histone H4

1

2

High-throughput

0.479

High

1089066

TP53B
TP53-binding protein 1

1

8

High-throughput

0.479

High

1129787

MDC1
Mediator of DNA damage checkpoint protein 1

1

12

High-throughput

0.479

High

1367580

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1437942

SP110
Sp110 nuclear body protein

1

9

High-throughput

0.479

High

1459300

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1461873

ASC
Apoptosis-associated speck-like protein containing a CARD

1

1

Small-scale

0.479

High

892736

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

1397550

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1384303

SH3K1
SH3 domain-containing kinase-binding protein 1

1

1

High-throughput

0.445

High

1430916

APC1
Anaphase-promoting complex subunit 1

1

3

High-throughput

0.445

High

273294

T22D2
TSC22 domain family protein 2

1

9

Small-scale

0.439

High

1022667

LRP2
Low-density lipoprotein receptor-related protein 2

1

3

Small-scale

0.439

High

1120589

LRP8
Low-density lipoprotein receptor-related protein 8

1

3

Small-scale

0.439

High

1310521

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

1194738

FBX43
F-box only protein 43

1

3

Small-scale

0.437

High

1434221

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High

430500

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

344368

PTBP3
Polypyrimidine tract-binding protein 3

1

8

High-throughput

0.407

High

261320

NSMA
Sphingomyelin phosphodiesterase 2

2

0

High-throughput

0.318

High

1244452

CP087
UPF0547 protein C16orf87

2

0

High-throughput

0.313

High

1103740

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

0

High-throughput

0.300

High

630380

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

1454471

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.279

Low

1290257

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.269

Low

49949

LNP1
Leukemia NUP98 fusion partner 1

1

0

Small-scale

0.249

Low

1040506

HHEX
Hematopoietically-expressed homeobox protein HHEX

1

0

Small-scale

0.249

Low

1392021

PLPR2
Phospholipid phosphatase-related protein type 2

1

0

High-throughput

0.249

Low

1411857

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025