HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 582
+	Hs
		1116542 PABP3_HUMAN (1-636): 0: 541: 91.37		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1031352 PABP4_HUMAN (1-635): 0: 534: 74.69		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116304 PAP1L_HUMAN (1-628): 9.51e-166: 489: 68.20		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		516689 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11
+	Hs
		516495 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516339 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		516568 PABP1_HUMAN (1-636): 0: 582: 100.00		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		516616 PABP1_HUMAN (1-636): 0: 582: 100.00		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		516635 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		403212 PABP4_HUMAN (1-635): 0: 534: 74.69		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Mm
		665745 PABP1_MOUSE (1-636): 0: 581: 99.69		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		1031407 PABP4_HUMAN (1-635): 0: 534: 74.69		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		474021 PABP4_HUMAN (1-635): 0: 534: 74.69		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		516561 PABP1_HUMAN (1-636): 0: 582: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1119141 PAP1L_HUMAN (1-628): 9.51e-166: 489: 68.20		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		1031367 PABP4_HUMAN (1-635): 0: 534: 74.69		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1031344 PABP4_HUMAN (1-635): 0: 534: 74.69		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Zm
		8143 A0A1D6ELH4_MAIZE (2-467): 9.33e-68: 235: 25.36		A0A1D6ELH4_MAIZE (2-130): 7.34e-12: 70.3: 10.69