HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: DCP1B (Q8IZD4)
mRNA-decapping enzyme 1B (EC 3.6.1.62)
Gene: DCP1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 617
+	Hs
		1031388 PABP4_HUMAN (1-635): 0: 534: 74.69		DCP1B_HUMAN (1-617): 6.91e-69: 237: 100.00
+	Hs
		516707 PABP1_HUMAN (1-636): 0: 582: 100.00		DCP1A_HUMAN (13-612): 5.51e-44: 167: 27.61
+	Hs
		1031472 PABP4_HUMAN (1-635): 0: 534: 74.69		DCP1A_HUMAN (13-612): 5.51e-44: 167: 27.61
+	Hs
		516476 PABP1_HUMAN (1-636): 0: 582: 100.00		IF4G1_HUMAN (117-572): 8.93e-23: 106: 8.79
+	Hs
		516595 PABP1_HUMAN (1-636): 0: 582: 100.00		KMT2C_HUMAN (124-592): 1.87e-09: 63.3: 10.78
+	Hs
		979889 PABP4_HUMAN (1-635): 0: 534: 74.69		IF4G1_HUMAN (117-572): 8.93e-23: 106: 8.79
+	Hs
		582147 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		SMCA4_HUMAN (212-616): 1.18e-26: 117: 9.09
+	Hs
		582292 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		MDC1_HUMAN (90-613): 3.95e-14: 78.3: 10.86
+	Hs
		582417 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		PRG4_HUMAN (114-599): 9.07e-10: 64.1: 8.69