Interactor 1: SIR4 (P11978)
Regulatory protein SIR4 (Silent information regulator 4)
Gene: SIR4

Interactor 2: ESC1 (Q03661)
Silent chromatin protein ESC1 (Establishes silent chromatin protein 1)
Gene: ESC1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.55 0.703

The method score is based on:

Property Details
Experiments 12417731, 24152732, 28883038, 31515872, 18086891, 21822217
Identification Methods two hybrid, affinity chromatography technology, x-ray crystallography, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0031509 - subtelomeric heterochromatin formation
GO:0034398 - telomere tethering at nuclear periphery
Homologous interactions 0

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Last updated: 15 Jul 2024