Protein: RCOR3
REST corepressor 3

Gene: RCOR3
Organism: Homo sapiens
Interactions: 181
UniProt ID: Q9P2K3

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0003714 - transcription corepressor activity
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1110137

HDAC1
Histone deacetylase 1

8

20

High-throughput

0.972

High

247001

KDM1A
Lysine-specific histone demethylase 1A

7

20

High-throughput

0.962

High

1368168

HDAC2
Histone deacetylase 2

5

20

High-throughput

0.925

High

1454666

RCOR1
REST corepressor 1

3

13

High-throughput

0.847

High

618127

K1C15
Keratin, type I cytoskeletal 15

4

5

High-throughput

0.710

High

188379

HDAC3
Histone deacetylase 3

1

20

High-throughput

0.691

High

1103423

CTBP1
C-terminal-binding protein 1

4

9

High-throughput

0.691

High

1353336

DOK4
Docking protein 4

4

4

High-throughput

0.691

High

1130671

GSE1
Genetic suppressor element 1

7

2

High-throughput

0.688

High

1146200

K1H1
Keratin, type I cuticular Ha1

3

6

High-throughput

0.675

High

1291372

LCA5
Lebercilin

3

4

High-throughput

0.675

High

350162

SNAI1
Zinc finger protein SNAI1

3

13

High-throughput

0.667

High

1454090

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

3

20

High-throughput

0.667

High

991745

DYL1
Dynein light chain 1, cytoplasmic

3

8

High-throughput

0.662

High

1132008

MVP
Major vault protein

3

1

High-throughput

0.662

High

1414243

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

3

7

High-throughput

0.662

High

1454670

NINL
Ninein-like protein

2

8

High-throughput

0.646

High

1090955

TRAF2
TNF receptor-associated factor 2

2

4

High-throughput

0.640

High

1454667

IKZF3
Zinc finger protein Aiolos

2

7

High-throughput

0.640

High

1241052

L2GL2
LLGL scribble cell polarity complex component 2

2

3

High-throughput

0.628

High

1415804

MAD3
Max dimerization protein 3

2

11

High-throughput

0.628

High

1454663

SMBT1
Scm-like with four MBT domains protein 1

2

16

High-throughput

0.628

High

1413353

MTA3
Metastasis-associated protein MTA3

1

13

High-throughput

0.618

High

848447

MAGA6
Melanoma-associated antigen 6

3

6

High-throughput

0.616

High

1063667

GOGA2
Golgin subfamily A member 2

3

7

High-throughput

0.616

High

1419245

TRI54
Tripartite motif-containing protein 54

3

7

High-throughput

0.616

High

1454665

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

9

High-throughput

0.616

High

1445898

HM20A
High mobility group protein 20A

3

20

High-throughput

0.616

High

426966

FGF1
Fibroblast growth factor 1

2

2

High-throughput

0.611

High

1454662

ZMYM2
Zinc finger MYM-type protein 2

2

6

High-throughput

0.611

High

848190

MAGA1
Melanoma-associated antigen 1

3

6

High-throughput

0.609

High

1327847

ARRD1
Arrestin domain-containing protein 1

3

3

High-throughput

0.609

High

300245

GLRX3
Glutaredoxin-3

2

1

High-throughput

0.606

High

437026

K1C18
Keratin, type I cytoskeletal 18

2

6

High-throughput

0.606

High

475714

K1C19
Keratin, type I cytoskeletal 19

2

5

High-throughput

0.606

High

659621

CRCM
Colorectal mutant cancer protein

2

2

High-throughput

0.606

High

1093986

TRAF1
TNF receptor-associated factor 1

2

1

High-throughput

0.606

High

1178758

K1C24
Keratin, type I cytoskeletal 24

2

6

High-throughput

0.606

High

1196333

GRAP1
GRIP1-associated protein 1

2

3

High-throughput

0.606

High

1210150

VAX1
Ventral anterior homeobox 1

2

18

High-throughput

0.606

High

1213596

PHF19
PHD finger protein 19

2

9

High-throughput

0.606

High

1238138

HMBX1
Homeobox-containing protein 1

2

16

High-throughput

0.606

High

1244649

GASP3
G protein-coupled receptor associated sorting protein 3

2

1

High-throughput

0.606

High

1277647

K1C27
Keratin, type I cytoskeletal 27

2

6

High-throughput

0.606

High

1316717

ABI1
Abl interactor 1

2

3

High-throughput

0.606

High

1350733

CCHCR
Coiled-coil alpha-helical rod protein 1

2

7

High-throughput

0.606

High

1388872

HOOK2
Protein Hook homolog 2

2

5

High-throughput

0.606

High

1398384

CEP63
Centrosomal protein of 63 kDa

2

7

High-throughput

0.606

High

1434837

STN1
CST complex subunit STN1

2

1

High-throughput

0.606

High

1454661

LHX3
LIM/homeobox protein Lhx3

2

8

High-throughput

0.606

High

1390737

DYL2
Dynein light chain 2, cytoplasmic

2

8

High-throughput

0.601

High

1206013

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

7

High-throughput

0.593

High

143302

NFIB
Nuclear factor 1 B-type

2

20

High-throughput

0.584

High

474342

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

269408

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

341870

K2C75
Keratin, type II cytoskeletal 75

2

0

High-throughput

0.580

High

1228577

HAUS3
HAUS augmin-like complex subunit 3

2

0

High-throughput

0.580

High

1332348

ZN383
Zinc finger protein 383

2

0

High-throughput

0.580

High

1361590

ING5
Inhibitor of growth protein 5

2

0

High-throughput

0.580

High

1416051

CC106
Coiled-coil domain-containing protein 106

2

0

High-throughput

0.580

High

1435948

NRDE2
Nuclear exosome regulator NRDE2

2

0

High-throughput

0.580

High

1454668

ISY1
Pre-mRNA-splicing factor ISY1 homolog

2

0

High-throughput

0.580

High

1389058

PF21B
PHD finger protein 21B

2

20

High-throughput

0.578

High

1218781

DC122
DDB1- and CUL4-associated factor 12-like protein 2

2

4

High-throughput

0.574

High

572258

TRI27
Zinc finger protein RFP

1

2

High-throughput

0.573

High

821216

TXLNA
Alpha-taxilin

1

6

High-throughput

0.573

High

1230294

K1C40
Keratin, type I cytoskeletal 40

1

6

High-throughput

0.573

High

1411355

LZTS2
Leucine zipper putative tumor suppressor 2

1

9

High-throughput

0.573

High

1429056

PRD14
PR domain zinc finger protein 14

1

1

High-throughput

0.573

High

1454660

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.573

High

51510

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

7

High-throughput

0.553

High

505776

ZN688
Zinc finger protein 688

2

4

High-throughput

0.553

High

1330106

USBP1
Harmonin-binding protein USHBP1

2

4

High-throughput

0.553

High

279526

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

326422

ZN202
Zinc finger protein 202

1

2

High-throughput

0.536

High

373374

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.536

High

384573

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.536

High

447882

TPM3
Tropomyosin alpha-3 chain

1

4

High-throughput

0.536

High

909220

NEK4
Serine/threonine-protein kinase Nek4

1

4

High-throughput

0.536

High

1123157

FHL2
Four and a half LIM domains protein 2

1

5

High-throughput

0.536

High

1152391

ZN174
Zinc finger protein 174

1

9

High-throughput

0.536

High

1411501

OVOL2
Transcription factor Ovo-like 2

1

10

High-throughput

0.536

High

1228733

C102B
Coiled-coil domain-containing protein 102B

1

1

High-throughput

0.523

High

1311481

TRI42
Tripartite motif-containing protein 42

1

12

High-throughput

0.523

High

1420314

TSG10
Testis-specific gene 10 protein

1

8

High-throughput

0.523

High

1340372

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.518

High

156087

SOCS6
Suppressor of cytokine signaling 6

1

2

High-throughput

0.515

High

1217772

GFI1B
Zinc finger protein Gfi-1b

1

7

Small-scale

0.515

High

374982

RASH
GTPase HRas

1

1

High-throughput

0.515

High

451291

NFL
Neurofilament light polypeptide

1

5

High-throughput

0.515

High

516906

ECE2
Endothelin-converting enzyme 2

2

2

High-throughput

0.504

High

423372

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

964485

SUMO2
Small ubiquitin-related modifier 2

1

9

High-throughput

0.501

High

442506

GELS
Gelsolin

1

0

High-throughput

0.493

High

954633

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

1279779

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

317755

NOL4
Nucleolar protein 4

1

2

High-throughput

0.489

High

1023425

AT11A
Phospholipid-transporting ATPase IH

1

1

High-throughput

0.489

High

1144258

PGFRL
Platelet-derived growth factor receptor-like protein

1

2

High-throughput

0.489

High

1332574

TEX19
Testis-expressed protein 19

1

1

High-throughput

0.489

High

1347785

F110D
Protein FAM110D

1

1

High-throughput

0.489

High

691504

1433T
14-3-3 protein theta

1

3

High-throughput

0.481

High

1247989

ANR11
Ankyrin repeat domain-containing protein 11

1

8

High-throughput

0.481

High

130643

SPT5H
Transcription elongation factor SPT5

1

7

High-throughput

0.479

High

181573

TBXT
T-box transcription factor T

1

13

High-throughput

0.479

High

225132

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

270280

MTG16
Protein CBFA2T3

1

5

Small-scale

0.479

High

277195

ZN217
Zinc finger protein 217

1

3

High-throughput

0.479

High

289185

PRDM1
PR domain zinc finger protein 1

1

4

High-throughput

0.479

High

404501

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

520415

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

590506

GATA1
Erythroid transcription factor

1

20

High-throughput

0.479

High

659311

SP100
Nuclear autoantigen Sp-100

1

20

High-throughput

0.479

High

662290

PAX7
Paired box protein Pax-7

1

16

High-throughput

0.479

High

662512

GATA2
Endothelial transcription factor GATA-2

1

20

High-throughput

0.479

High

662665

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

20

High-throughput

0.479

High

685369

PAX6
Paired box protein Pax-6

1

12

High-throughput

0.479

High

703210

TEAD1
Transcriptional enhancer factor TEF-1

1

2

High-throughput

0.479

High

725331

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

776142

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

776260

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

834076

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

872833

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

937948

FOXA1
Hepatocyte nuclear factor 3-alpha

1

17

High-throughput

0.479

High

944755

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

980470

H4
Histone H4

1

6

High-throughput

0.479

High

1054805

SUH
Recombining binding protein suppressor of hairless

1

3

High-throughput

0.479

High

1088070

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1091260

FOXI1
Forkhead box protein I1

1

14

High-throughput

0.479

High

1091364

FOXL1
Forkhead box protein L1

1

15

High-throughput

0.479

High

1123614

ZMYM3
Zinc finger MYM-type protein 3

1

6

High-throughput

0.479

High

1133706

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1137560

SUZ12
Polycomb protein SUZ12

1

4

High-throughput

0.479

High

1140975

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1155850

EZH2
Histone-lysine N-methyltransferase EZH2

1

18

High-throughput

0.479

High

1295167

PHF13
PHD finger protein 13

1

1

High-throughput

0.479

High

1351182

SP7
Transcription factor Sp7

1

14

High-throughput

0.479

High

1359712

PHIP
PH-interacting protein

1

18

High-throughput

0.479

High

1363999

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

2

High-throughput

0.479

High

1384462

PF21A
PHD finger protein 21A

1

20

High-throughput

0.479

High

1395255

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

16

High-throughput

0.479

High

1402330

RANB9
Ran-binding protein 9

1

2

Small-scale

0.479

High

1420510

FOXQ1
Forkhead box protein Q1

1

18

High-throughput

0.479

High

1445867

GCM1
Chorion-specific transcription factor GCMa

1

2

High-throughput

0.479

High

1454669

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

20

High-throughput

0.479

High

1454671

KLF12
Krueppel-like factor 12

1

17

High-throughput

0.479

High

246170

KIF1B
Kinesin-like protein KIF1B

1

5

High-throughput

0.470

High

650464

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.470

High

1454673

X5D778
Ankyrin repeat domain 11 isoform A

1

17

High-throughput

0.470

High

1397123

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

911415

IMA5
Importin subunit alpha-5

1

13

High-throughput

0.445

High

1428253

TGIF2
Homeobox protein TGIF2

1

3

High-throughput

0.445

High

106780

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

294462

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

391100

TRFL
Lactotransferrin

1

1

High-throughput

0.437

High

1247639

SAMD1
Sterile alpha motif domain-containing protein 1

1

4

High-throughput

0.437

High

1258403

MOB3C
MOB kinase activator 3C

1

3

High-throughput

0.437

High

1383698

VP33A
Vacuolar protein sorting-associated protein 33A

1

2

High-throughput

0.437

High

1445959

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

8

High-throughput

0.437

High

1454664

XPO7
Exportin-7

1

3

High-throughput

0.437

High

3587

A0A0S2Z615
PHD finger protein 21B isoform 3

1

5

High-throughput

0.417

High

1279987

NECA2
N-terminal EF-hand calcium-binding protein 2

4

0

High-throughput

0.365

High

665740

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

4

0

High-throughput

0.360

High

1163712

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

2

0

High-throughput

0.328

High

605491

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

1131244

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

1206443

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1217457

GKAP1
G kinase-anchoring protein 1

2

0

High-throughput

0.316

High

1332447

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

1336666

ICA1L
Islet cell autoantigen 1-like protein

2

0

High-throughput

0.316

High

1348876

FA81A
Protein FAM81A

2

0

High-throughput

0.316

High

1392359

BORC6
BLOC-1-related complex subunit 6

2

0

High-throughput

0.316

High

1451297

PIHD1
PIH1 domain-containing protein 1

2

0

High-throughput

0.316

High

1453252

PTTG2
Securin-2

2

0

High-throughput

0.316

High

1033437

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.299

High

1198542

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.299

High

1350369

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.299

High

1454111

LUZP4
Leucine zipper protein 4

1

0

High-throughput

0.299

High

301742

WFS1
Wolframin

1

0

High-throughput

0.268

Low

1454672

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1294635

NUTM1
NUT family member 1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025