Protein: ECE2
Endothelin-converting enzyme 2 (ECE-2) (EC 3.4.24.71)

Gene: ECE2
Organism: Homo sapiens
Interactions: 18
UniProt ID: P0DPD6

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004222 - metalloendopeptidase activity
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007267 - cell-cell signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

516899

KCIP4
Kv channel-interacting protein 4

2

0

High-throughput

0.528

High

516895

CD53
Leukocyte surface antigen CD53

1

8

High-throughput

0.515

High

516906

RCOR3
REST corepressor 3

2

2

High-throughput

0.504

High

516907

RCOR1
REST corepressor 1

2

2

High-throughput

0.504

High

516902

LMO7
LIM domain only protein 7

1

2

High-throughput

0.445

High

516905

MUC5B
Mucin-5B

1

2

High-throughput

0.445

High

516903

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.426

High

370056

CYTS
Cystatin-S

1

3

High-throughput

0.407

High

479911

CYTT
Cystatin-SA

1

3

High-throughput

0.407

High

516896

PEX5
Peroxisomal targeting signal 1 receptor

1

2

High-throughput

0.407

High

516897

KS6A3
Ribosomal protein S6 kinase alpha-3

1

3

High-throughput

0.407

High

516898

KS6A2
Ribosomal protein S6 kinase alpha-2

1

3

High-throughput

0.407

High

516901

RCOR2
REST corepressor 2

1

2

High-throughput

0.407

High

246406

KDM1A
Lysine-specific histone demethylase 1A

2

0

High-throughput

0.288

High

516900

DHX40
Probable ATP-dependent RNA helicase DHX40

2

0

High-throughput

0.288

High

516904

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.238

Low

62738

PI4P2
Putative phosphatidylinositol 4-kinase alpha-like protein P2

1

0

High-throughput

0.232

Low

516894

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025