Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: POLH (Q9Y253)
DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)
Gene: POLH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 24474685, 27770570, 26988343, 30963698, 11585903, 31796584, 20159558, 16763556, 23042605, 23761444, 23388460, 20129057, 25766642, 28831681, 30563767, 15149598, 21791603, 21855803, 15342632, 23345618
Identification Methods pull down, fluorescent resonance energy transfer, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IMS_C~PCNA_N
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005657 - replication fork
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 261
Hs

1 713
+ Hs
+ Mm
+ At
+ At
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Sp
+ Ce
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024