HitPredict

Interactor 1: K2C3 (P12035)
Keratin, type II cytoskeletal 3 (65 kDa cytokeratin) (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (Type-II keratin Kb3)
Gene: KRT3

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27507811
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 628 Hs			1 522
+	Hs
		729200 K22E_HUMAN (170-516): 5.85e-174: 510: 72.49		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		409288 K2C8_HUMAN (170-550): 6.7e-164: 479: 65.35		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		380708 K2C1_HUMAN (163-531): 1.13e-105: 334: 73.44		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		301654 K22E_HUMAN (170-516): 5.85e-174: 510: 72.49		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		409276 K2C8_HUMAN (170-550): 6.7e-164: 479: 65.35		PZRN3_HUMAN (55-366): 6.23e-48: 180: 20.31
+	Hs
		729167 K22E_HUMAN (170-516): 5.85e-174: 510: 72.49		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00
+	Hs
		301540 K2C8_HUMAN (170-550): 6.7e-164: 479: 65.35		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		301560 K2C7_HUMAN (140-527): 5.2e-149: 440: 63.94		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Mm
		1141443 KRT81_MOUSE (77-515): 7.76e-84: 272: 49.89		TRAF3_MOUSE (20-501): 4.18e-85: 275: 22.40
+	Mm
		957023 KRT86_MOUSE (81-521): 4.3e-83: 271: 49.66		TRAF3_MOUSE (20-501): 4.18e-85: 275: 22.40
+	Mm
		1141414 KRT87_MOUSE (77-586): 3.44e-82: 269: 45.29		TRAF3_MOUSE (20-501): 4.18e-85: 275: 22.40
+	Hs
		301526 K2C1_HUMAN (163-531): 1.13e-105: 334: 73.44		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		380552 K2C1_HUMAN (163-531): 1.13e-105: 334: 73.44		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		318801 K2C75_HUMAN (36-586): 3.14e-82: 271: 56.62		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		517750 K2C3_HUMAN (1-628): 1.78e-76: 257: 100.00		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		380682 K2C1_HUMAN (163-531): 1.13e-105: 334: 73.44		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00
+	Hs
		318774 K2C75_HUMAN (36-586): 3.14e-82: 271: 56.62		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		301525 K2C6B_HUMAN (36-537): 5.85e-76: 254: 64.54		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		517736 K2C3_HUMAN (1-628): 1.78e-76: 257: 100.00		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		380469 K2C6B_HUMAN (36-537): 5.85e-76: 254: 64.54		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59