HitPredict

Interactor 1: TPR (P12270)
Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)
Gene: TPR

Interactor 2: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26549023
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2363 Hs			1 595
+	Hs
		518823 TPR_HUMAN (1-2351): 7.93e-175: 597: 100.00		PTN4_HUMAN (1-515): 8.77e-124: 388: 21.09
+	Hs
		640146 CP250_HUMAN (190-2334): 9.64e-69: 260: 10.18		MOES_HUMAN (19-595): 5.97e-146: 435: 44.44
+	Hs
		719681 CENPF_HUMAN (270-2309): 1.3e-43: 178: 10.34		RADI_HUMAN (19-595): 5.41e-151: 448: 45.47
+	Hs
		547271 MYH13_HUMAN (1098-2165): 8.48e-35: 149: 10.63		EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20
+	Hs
		148455 CTRO_HUMAN (1173-1646): 8.14e-09: 63.5: 22.34		MERL_HUMAN (1-595): 1.12e-172: 504: 100.00
+	Hs
		640054 MYH9_HUMAN (1404-2309): 4.5e-28: 127: 9.29		MOES_HUMAN (19-595): 5.97e-146: 435: 44.44
+	Hs
		547057 GOGB1_HUMAN (1154-2305): 3.59e-23: 110: 8.33		EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20
+	Hs
		505542 MYH1_HUMAN (1204-2274): 3.68e-38: 160: 10.14		EPB41_HUMAN (3-566): 9.71e-126: 392: 19.73
+	Hs
		640102 GOGB1_HUMAN (1154-2305): 3.59e-23: 110: 8.33		MOES_HUMAN (19-595): 5.97e-146: 435: 44.44
+	Hs
		505568 MYH9_HUMAN (1404-2309): 4.5e-28: 127: 9.29		EPB41_HUMAN (3-566): 9.71e-126: 392: 19.73
+	Hs
		148355 CTRO_HUMAN (1173-1646): 8.14e-09: 63.5: 22.34		EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20
+	Hs
		640122 CNTRL_HUMAN (2-538): 3.64e-12: 74.7: 12.68		MOES_HUMAN (19-595): 5.97e-146: 435: 44.44
+	Hs
		640092 CENPE_HUMAN (1504-2319): 3.1e-10: 68.2: 7.39		MOES_HUMAN (19-595): 5.97e-146: 435: 44.44
+	Hs
		1331065 MYH4_HUMAN (1417-2325): 2.22e-27: 124: 8.16		E41L1_HUMAN (1-535): 3.42e-120: 378: 21.61
+	Hs
		505569 MYH10_HUMAN (2-563): 2.37e-21: 104: 15.02		EPB41_HUMAN (3-566): 9.71e-126: 392: 19.73
+	Hs
		505634 NUMA1_HUMAN (1475-2060): 2.53e-11: 72: 10.08		EPB41_HUMAN (3-566): 9.71e-126: 392: 19.73
+	Hs
		1061246 NUMA1_HUMAN (1475-2060): 2.53e-11: 72: 10.08		E41L1_HUMAN (1-535): 3.42e-120: 378: 21.61
+	Hs
		1061296 NUMA1_HUMAN (1475-2060): 2.53e-11: 72: 10.08		E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04
+	Hs
		204667 NUMA1_HUMAN (1475-2060): 2.53e-11: 72: 10.08		E41L2_HUMAN (11-519): 9e-113: 361: 19.70
+	Hs
		148997 CTRO_HUMAN (1173-1646): 8.14e-09: 63.5: 22.34		FRMD5_HUMAN (9-358): 3.53e-113: 350: 26.20