HitPredict

Interactor 1: TPR (P12270)
Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)
Gene: TPR

Interactor 2: MD2L1 (Q13257)
Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)
Gene: MAD2L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	33961781, 24938596
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0007094 - mitotic spindle assembly checkpoint signaling and 5 others more... GO:0042803 - protein homodimerization activity GO:0044615 - nuclear pore nuclear basket GO:0051301 - cell division GO:0072686 - mitotic spindle GO:0090267 - positive regulation of mitotic cell cycle spindle assembly checkpoint
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	2363
Hs

1	205

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024