HitPredict

Interactor 1: FCGR1 (P12314)
High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64)
Gene: FCGR1A

Interactor 2: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 374 Hs			1 4008
+	Hs
		519338 FCGR1_HUMAN (1-374): 1.3e-99: 301: 100.00		FREM2_HUMAN (1296-3338): 2.12e-108: 393: 18.62
+	Hs
		519331 FCGR1_HUMAN (1-374): 1.3e-99: 301: 100.00		PCDH1_HUMAN (2678-3411): 7.66e-49: 194: 10.88
+	Hs
		970116 CNTN2_HUMAN (20-341): 1.65e-40: 154: 13.03		CSPG4_HUMAN (1594-2898): 4.17e-72: 273: 17.50
+	Hs
		252750 FCG3B_HUMAN (99-317): 1.23e-33: 126: 16.14		CSPG4_HUMAN (1594-2898): 4.17e-72: 273: 17.50
+	Hs
		798234 KI3L1_HUMAN (5-351): 7.29e-53: 183: 18.02		PCDH1_HUMAN (2678-3411): 7.66e-49: 194: 10.88
+	Hs
		519357 FCGR1_HUMAN (1-374): 1.3e-99: 301: 100.00		CELR2_HUMAN (985-1093): 1.37e-10: 70.4: 16.36
+	Hs
		980365 CNTN1_HUMAN (1-342): 3.17e-47: 174: 15.04		NOTC2_HUMAN (567-1139): 7.18e-39: 163: 13.53
+	Hs
		804225 CNTN1_HUMAN (1-342): 3.17e-47: 174: 15.04		NOTC1_HUMAN (5-694): 7.39e-38: 160: 13.02
+	Hs
		980481 PXDN_HUMAN (175-373): 5.51e-26: 111: 12.28		NOTC2_HUMAN (567-1139): 7.18e-39: 163: 13.53
+	Dm
		422809 Q9BN17_DROME (32-279): 3.04e-14: 76.2: 22.18		NOTCH_DROME (650-1139): 1.68e-29: 132: 11.58
+	Hs
		1268531 PXDN_HUMAN (175-373): 5.51e-26: 111: 12.28		NELL2_HUMAN (23-499): 1.93e-09: 66.2: 22.65
+	Hs
		1268526 PXDN_HUMAN (175-373): 5.51e-26: 111: 12.28		NELL1_HUMAN (157-646): 2.78e-09: 65.5: 22.39
+	Hs
		1298001 ROBO3_HUMAN (14-119): 2.37e-14: 76.7: 17.54		NELL2_HUMAN (23-499): 1.93e-09: 66.2: 22.65
+	Dm
		1213857 Q9BN17_DROME (32-279): 3.04e-14: 76.2: 22.18		Q8IP51_DROME (421-663): 4.6e-09: 65.3: 18.47
+	Hs
		631060 PGBM_HUMAN (103-175): 8.14e-09: 59.7: 13.25		LAMA1_HUMAN (865-1036): 6.38e-09: 64.9: 18.09