HitPredict

Interactor 1: PDR1 (P12383)
Transcription factor PDR1 (Pleiotropic drug resistance protein 1)
Gene: PDR1

Interactor 2: MED15 (P19659)
Mediator of RNA polymerase II transcription subunit 15 (Autonomous replication regulatory protein 3) (Basal expression activator protein 1) (Defective silencing suppressor protein 4) (Mediator complex subunit 15) (Transcription regulatory protein GAL11) (Ty insertion suppressor protein 13)
Gene: GAL11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	18385733, 20505076
Identification Methods	pull down, nuclear magnetic resonance, anti tag coimmunoprecipitation, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 1068 Sc			1 1081
+	Sc
		586280 PDR3_YEAST (34-1063): 0: 1307: 32.57		MED15_YEAST (1-1081): 0: 1590: 100.00