Protein: OSTP
Osteopontin (Bone sialoprotein 1) (Nephropontin) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Uropontin)

Gene: OSTP, SPP1
Organism: Homo sapiens
Interactions: 98
UniProt ID: P10451

Gene Ontology (top 5):
GO:0001649 - osteoblast differentiation
GO:0005125 - cytokine activity
GO:0005178 - integrin binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

213464

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

5

1

Small-scale

0.664

High

489573

BAG6
Large proline-rich protein BAG6

3

2

Small-scale

0.654

High

489602

FA20C
Extracellular serine/threonine protein kinase FAM20C

3

1

Small-scale

0.651

High

489622

UBQL4
Ubiquilin-4

2

1

Small-scale

0.613

High

489580

NCS1
Neuronal calcium sensor 1

2

1

High-throughput

0.606

High

210880

GET3
ATPase GET3

2

0

High-throughput

0.580

High

489610

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

1

High-throughput

0.553

High

383555

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

0

High-throughput

0.551

High

489568

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

Small-scale

0.536

High

489558

PEPD
Xaa-Pro dipeptidase

1

0

High-throughput

0.518

High

489577

CCR8
C-C chemokine receptor type 8

1

0

High-throughput

0.518

High

403747

ITB1
Integrin beta-1

1

1

Small-scale

0.501

High

489562

ITB5
Integrin beta-5

1

1

Small-scale

0.501

High

489612

FA20A
Pseudokinase FAM20A

1

1

Small-scale

0.501

High

489572

CASP3
Caspase-3

1

1

Small-scale

0.490

High

489589

CASP8
Caspase-8

1

1

Small-scale

0.490

High

489575

MAP1B
Microtubule-associated protein 1B

1

3

Small-scale

0.481

High

419141

ITAV
Integrin alpha-V

1

0

Small-scale

0.480

High

489565

IBP5
Insulin-like growth factor-binding protein 5

1

0

Small-scale

0.480

High

310893

SNAPN
SNARE-associated protein Snapin

1

0

Small-scale

0.460

High

322107

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

Small-scale

0.460

High

335346

NB5R3
NADH-cytochrome b5 reductase 3

1

0

Small-scale

0.460

High

361306

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.460

High

365134

FRIH
Ferritin heavy chain

1

0

Small-scale

0.460

High

427982

TBB5
Tubulin beta chain

1

0

Small-scale

0.460

High

489559

TCTP
Translationally-controlled tumor protein

1

0

Small-scale

0.460

High

489561

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

0

Small-scale

0.460

High

489563

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

0

Small-scale

0.460

High

489566

DNJB1
DnaJ homolog subfamily B member 1

1

0

Small-scale

0.460

High

489569

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

Small-scale

0.460

High

489574

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.460

High

489581

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.460

High

489582

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.460

High

489583

HBA
Hemoglobin subunit alpha

1

0

Small-scale

0.460

High

489588

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

Small-scale

0.460

High

489601

PLD3
5'-3' exonuclease PLD3

1

0

Small-scale

0.460

High

489607

NICA
Nicastrin

1

0

Small-scale

0.460

High

489609

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.460

High

489613

CKLF3
CKLF-like MARVEL transmembrane domain-containing protein 3

1

0

Small-scale

0.460

High

489624

CC50A
Cell cycle control protein 50A

1

0

Small-scale

0.460

High

489626

C1RL
Complement C1r subcomponent-like protein

1

0

Small-scale

0.460

High

489632

NCKP1
Nck-associated protein 1

1

0

Small-scale

0.460

High

489634

RPGF2
Rap guanine nucleotide exchange factor 2

1

0

Small-scale

0.460

High

129663

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

455021

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

489608

RSCA1
Regulatory solute carrier protein family 1 member 1

1

0

Small-scale

0.458

High

489584

MAP1A
Microtubule-associated protein 1A

1

3

Small-scale

0.439

High

489590

ZN638
Zinc finger protein 638

1

1

Small-scale

0.439

High

489615

TTC1
Tetratricopeptide repeat protein 1

1

2

Small-scale

0.439

High

489625

KCIP1
Kv channel-interacting protein 1

1

1

Small-scale

0.439

High

489576

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

489560

DRD2
D(2) dopamine receptor

1

0

High-throughput

0.282

High

489570

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

0

High-throughput

0.282

High

489606

CTBL1
Beta-catenin-like protein 1

1

0

High-throughput

0.282

High

489621

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.282

High

151374

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

0

Small-scale

0.251

Low

173336

S22A1
Solute carrier family 22 member 1

1

0

Small-scale

0.251

Low

179429

MPPD1
Metallophosphoesterase domain-containing protein 1

1

0

Small-scale

0.251

Low

208238

DCX
Neuronal migration protein doublecortin

1

0

Small-scale

0.251

Low

321268

TBCD8
TBC1 domain family member 8

1

0

Small-scale

0.251

Low

396872

HMGN1
Non-histone chromosomal protein HMG-14

1

0

Small-scale

0.251

Low

403068

LA
Lupus La protein

1

0

Small-scale

0.251

Low

489564

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

0

Small-scale

0.251

Low

489567

RL13
Large ribosomal subunit protein eL13

1

0

Small-scale

0.251

Low

489571

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

Small-scale

0.251

Low

489578

SC24C
Protein transport protein Sec24C

1

0

Small-scale

0.251

Low

489579

RL15
Large ribosomal subunit protein eL15

1

0

Small-scale

0.251

Low

489587

S39A6
Zinc transporter ZIP6

1

0

Small-scale

0.251

Low

489592

BRD3
Bromodomain-containing protein 3

1

0

Small-scale

0.251

Low

489594

RM23
Large ribosomal subunit protein uL23m

1

0

Small-scale

0.251

Low

489595

GRAP1
GRIP1-associated protein 1

1

0

Small-scale

0.251

Low

489596

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

Small-scale

0.251

Low

489597

C2D1B
Coiled-coil and C2 domain-containing protein 1B

1

0

Small-scale

0.251

Low

489598

CE162
Centrosomal protein of 162 kDa

1

0

Small-scale

0.251

Low

489599

Z804A
Zinc finger protein 804A

1

0

Small-scale

0.251

Low

489600

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

0

Small-scale

0.251

Low

489603

DSEL
Dermatan-sulfate epimerase-like protein

1

0

Small-scale

0.251

Low

489604

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

Small-scale

0.251

Low

489605

COMD1
COMM domain-containing protein 1

1

0

Small-scale

0.251

Low

489611

CB050
Uncharacterized protein C2orf50

1

0

Small-scale

0.251

Low

489614

RANB9
Ran-binding protein 9

1

0

Small-scale

0.251

Low

489616

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.251

Low

489617

TM168
Transmembrane protein 168

1

0

Small-scale

0.251

Low

489618

RIMS4
Regulating synaptic membrane exocytosis protein 4

1

0

Small-scale

0.251

Low

489619

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

0

Small-scale

0.251

Low

489620

LRRC4
Leucine-rich repeat-containing protein 4

1

0

Small-scale

0.251

Low

489627

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

Small-scale

0.251

Low

489628

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

Small-scale

0.251

Low

489629

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

Small-scale

0.251

Low

489630

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

0

Small-scale

0.251

Low

489631

AFF4
AF4/FMR2 family member 4

1

0

Small-scale

0.251

Low

489633

AMOL2
Angiomotin-like protein 2

1

0

Small-scale

0.251

Low

489585

TRAF3
TNF receptor-associated factor 3

1

0

Small-scale

0.249

Low

489586

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.249

Low

489591

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low

489593

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

489623

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.238

Low

126187

PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024