Protein: FOXP1
Forkhead box protein P1 (Mac-1-regulated forkhead) (MFH)

Gene: FOXP1
Organism: Homo sapiens
Interactions: 133
UniProt ID: Q9H334

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001046 - core promoter sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

190091

FOXP2
Forkhead box protein P2

9

17

Small-scale

0.971

High

1308724

FOXP4
Forkhead box protein P4

4

17

Small-scale

0.886

High

1420198

FOXP3
Forkhead box protein P3

3

16

High-throughput

0.871

High

1432488

FOXP1
Forkhead box protein P1

4

17

Small-scale

0.867

High

1091058

FOXF1
Forkhead box protein F1

1

19

High-throughput

0.691

High

1432495

ZMYM2
Zinc finger MYM-type protein 2

2

11

Small-scale

0.646

High

1032782

SATB1
DNA-binding protein SATB1

2

20

Small-scale

0.639

High

1432499

SATB2
DNA-binding protein SATB2

2

20

Small-scale

0.639

High

776128

SOX5
Transcription factor SOX-5

2

20

Small-scale

0.624

High

321987

NFAT5
Nuclear factor of activated T-cells 5

1

17

Small-scale

0.618

High

540949

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.618

High

837089

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.618

High

1091155

FOXC1
Forkhead box protein C1

1

19

Small-scale

0.618

High

1091249

FOXI1
Forkhead box protein I1

1

18

High-throughput

0.618

High

1091343

FOXL1
Forkhead box protein L1

1

19

High-throughput

0.618

High

1405432

FEV
Protein FEV

1

20

High-throughput

0.618

High

414608

P53
Cellular tumor antigen p53

2

12

Small-scale

0.611

High

941553

CTBP2
C-terminal-binding protein 2

2

8

High-throughput

0.611

High

1182862

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

2

High-throughput

0.602

High

143250

NFIB
Nuclear factor 1 B-type

2

20

High-throughput

0.584

High

474285

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

520371

ANDR
Androgen receptor

2

20

Small-scale

0.584

High

1088013

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

1133657

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

1361008

P66B
Transcriptional repressor p66-beta

2

5

Small-scale

0.584

High

1103371

CTBP1
C-terminal-binding protein 1

2

8

Small-scale

0.571

High

170346

AURKA
Aurora kinase A

1

1

Small-scale

0.561

High

522836

COT1
COUP transcription factor 1

1

20

Small-scale

0.561

High

665141

COT2
COUP transcription factor 2

1

20

Small-scale

0.561

High

675673

TYY1
Transcriptional repressor protein YY1

1

8

Small-scale

0.561

High

1104671

IKZF1
DNA-binding protein Ikaros

1

9

Small-scale

0.561

High

1432501

NCOR2
Nuclear receptor corepressor 2

1

17

Small-scale

0.561

High

289172

PRDM1
PR domain zinc finger protein 1

2

0

Small-scale

0.559

High

908785

MAT1
CDK-activating kinase assembly factor MAT1

1

0

High-throughput

0.536

High

373133

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.536

High

473080

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

5

High-throughput

0.536

High

542650

TOP2A
DNA topoisomerase 2-alpha

1

3

High-throughput

0.536

High

589665

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.536

High

616366

RCC1
Regulator of chromosome condensation

1

3

High-throughput

0.536

High

617739

XRCC1
DNA repair protein XRCC1

1

2

High-throughput

0.536

High

628841

TBP
TATA-box-binding protein

1

5

High-throughput

0.536

High

765028

CTNB1
Catenin beta-1

1

8

High-throughput

0.536

High

1432492

UBIP1
Upstream-binding protein 1

1

13

High-throughput

0.536

High

769157

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.536

High

773275

MYH10
Myosin-10

1

2

High-throughput

0.536

High

814865

CUX1
Homeobox protein cut-like 1

1

20

High-throughput

0.536

High

839368

MTOR
Serine/threonine-protein kinase mTOR

1

7

High-throughput

0.536

High

892621

DNLI3
DNA ligase 3

1

4

High-throughput

0.536

High

926410

BLM
RecQ-like DNA helicase BLM

1

6

High-throughput

0.536

High

1086313

TFCP2
Alpha-globin transcription factor CP2

1

13

High-throughput

0.536

High

1123112

FHL2
Four and a half LIM domains protein 2

1

7

High-throughput

0.536

High

1144157

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1292513

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

20

High-throughput

0.536

High

1308484

VRK3
Serine/threonine-protein kinase VRK3

1

6

High-throughput

0.536

High

1387841

ZBT10
Zinc finger and BTB domain-containing protein 10

1

20

High-throughput

0.536

High

1432491

SALL1
Sal-like protein 1

1

8

High-throughput

0.536

High

1432498

TTF2
Transcription termination factor 2

1

20

High-throughput

0.536

High

892941

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.513

High

169140

ML12B
Myosin regulatory light chain 12B

1

4

High-throughput

0.489

High

666766

MYL9
Myosin regulatory light polypeptide 9

1

4

High-throughput

0.489

High

1178150

QSER1
Glutamine and serine-rich protein 1

1

16

High-throughput

0.489

High

939480

RAG2
V(D)J recombination-activating protein 2

1

0

Small-scale

0.480

High

129421

MEN1
Menin

1

3

High-throughput

0.479

High

176308

ZBT39
Zinc finger and BTB domain-containing protein 39

1

4

Small-scale

0.479

High

181563

TBXT
T-box transcription factor T

1

8

High-throughput

0.479

High

210114

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

225108

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

239997

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.479

High

242906

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

320922

TOX
Thymocyte selection-associated high mobility group box protein TOX

1

20

Small-scale

0.479

High

339854

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

342319

BRD1
Bromodomain-containing protein 1

1

13

High-throughput

0.479

High

538470

EGR2
E3 SUMO-protein ligase EGR2

1

5

High-throughput

0.479

High

607104

CEBPB
CCAAT/enhancer-binding protein beta

1

5

Small-scale

0.479

High

639820

TAF1
Transcription initiation factor TFIID subunit 1

1

20

High-throughput

0.479

High

651102

RFX1
MHC class II regulatory factor RFX1

1

20

Small-scale

0.479

High

659301

SP100
Nuclear autoantigen Sp-100

1

20

High-throughput

0.479

High

662277

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

662498

GATA2
Endothelial transcription factor GATA-2

1

15

High-throughput

0.479

High

685347

PAX6
Paired box protein Pax-6

1

18

High-throughput

0.479

High

703198

TEAD1
Transcriptional enhancer factor TEF-1

1

2

High-throughput

0.479

High

725317

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

771613

HXD13
Homeobox protein Hox-D13

1

20

High-throughput

0.479

High

775911

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

776248

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

834053

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

872741

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

887218

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

887465

CEBPD
CCAAT/enhancer-binding protein delta

1

5

Small-scale

0.479

High

895797

LHX2
LIM/homeobox protein Lhx2

1

16

High-throughput

0.479

High

903481

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.479

High

938503

PAX9
Paired box protein Pax-9

1

13

High-throughput

0.479

High

942465

GSC
Homeobox protein goosecoid

1

20

High-throughput

0.479

High

944739

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

1040079

PAX2
Paired box protein Pax-2

1

17

High-throughput

0.479

High

1056649

PAX8
Paired box protein Pax-8

1

19

High-throughput

0.479

High

1102650

MTA1
Metastasis-associated protein MTA1

1

10

Small-scale

0.479

High

1115055

CUL4A
Cullin-4A

1

5

High-throughput

0.479

High

1115422

CUL4B
Cullin-4B

1

5

High-throughput

0.479

High

1118777

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

1122868

TFDP1
Transcription factor Dp-1

1

2

Small-scale

0.479

High

1153908

SMAD2
Mothers against decapentaplegic homolog 2

1

8

Small-scale

0.479

High

1252583

BNC2
Zinc finger protein basonuclin-2

1

2

Small-scale

0.479

High

1278974

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

16

Small-scale

0.479

High

1287985

PB1
Protein polybromo-1

1

13

Small-scale

0.479

High

1288848

ZFHX4
Zinc finger homeobox protein 4

1

9

Small-scale

0.479

High

1323539

ZN687
Zinc finger protein 687

1

2

Small-scale

0.479

High

1328951

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

2

Small-scale

0.479

High

1351160

SP7
Transcription factor Sp7

1

17

High-throughput

0.479

High

1359700

PHIP
PH-interacting protein

1

16

High-throughput

0.479

High

1367258

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1380008

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

11

Small-scale

0.479

High

1382841

FUBP1
Far upstream element-binding protein 1

1

13

Small-scale

0.479

High

1394775

HIC2
Hypermethylated in cancer 2 protein

1

4

Small-scale

0.479

High

1404394

CDC5L
Cell division cycle 5-like protein

1

3

Small-scale

0.479

High

1413228

SOX7
Transcription factor SOX-7

1

20

High-throughput

0.479

High

1416906

KLF16
Krueppel-like factor 16

1

18

High-throughput

0.479

High

1432489

GCM1
Chorion-specific transcription factor GCMa

1

1

High-throughput

0.479

High

1432493

VSX1
Visual system homeobox 1

1

20

High-throughput

0.479

High

1432494

LHX3
LIM/homeobox protein Lhx3

1

12

High-throughput

0.479

High

1432496

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1432497

SOX13
Transcription factor SOX-13

1

20

Small-scale

0.479

High

1432500

ZN148
Zinc finger protein 148

1

5

Small-scale

0.479

High

1054789

SUH
Recombining binding protein suppressor of hairless

1

0

Small-scale

0.458

High

1352748

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

725190

HXC13
Homeobox protein Hox-C13

1

20

High-throughput

0.445

High

1326088

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

1213042

CC183
Coiled-coil domain-containing protein 183

3

0

High-throughput

0.347

High

689965

IL3RA
Interleukin-3 receptor subunit alpha

1

0

High-throughput

0.282

High

1401804

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.279

Low

1431166

N62CL
Nucleoporin-62 C-terminal-like protein

1

0

High-throughput

0.279

Low

1432490

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025