HitPredict

Interactor 1: MYCL (P12524)
Protein L-Myc (Class E basic helix-loop-helix protein 38) (bHLHe38) (Protein L-Myc-1) (V-myc myelocytomatosis viral oncogene homolog)
Gene: MYCL

Interactor 2: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 364 Hs			1 513
+	Mm
		348441 MYC_MOUSE (1-362): 4.56e-78: 248: 29.98		KAT5_MOUSE (1-513): 0: 852: 99.81
+	Hs
		347509 MYC_HUMAN (1-362): 1e-76: 245: 29.75		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Hs
		379684 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Mm
		659351 MAX_MOUSE (278-362): 1.42e-21: 92: 34.12		KAT5_MOUSE (1-513): 0: 852: 99.81
+	Hs
		898167 MAX_HUMAN (278-362): 3.89e-21: 90.8: 34.12		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Hs
		347907 MYC_HUMAN (1-362): 1e-76: 245: 29.75		KAT8_HUMAN (162-504): 3.51e-168: 485: 46.67
+	Hs
		309640 MYC_HUMAN (1-362): 1e-76: 245: 29.75		KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30