HitPredict

Interactor 1: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Interactor 2: HOG1 (P32485)
Mitogen-activated protein kinase HOG1 (MAP kinase HOG1) (EC 2.7.11.24) (High osmolarity glycerol response protein 1)
Gene: HOG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29738528
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 559 Sc			1 435
+	Sc
		691051 TCPG_YEAST (7-552): 0: 537: 28.75		HOG1_YEAST (1-435): 2.33e-166: 476: 100.00
+	Hs
		625228 TCPG_HUMAN (4-555): 0: 575: 29.53		CDK2_HUMAN (20-308): 5.17e-152: 434: 36.95
+	Sc
		691072 TCPH_YEAST (1-555): 0: 531: 31.00		HOG1_YEAST (1-435): 2.33e-166: 476: 100.00
+	Rn
		600455 TCPE_RAT (17-551): 0: 605: 29.55		MK03_RAT (14-351): 2.43e-137: 400: 45.98
+	Hs
		573132 TCPA_HUMAN (9-556): 0: 569: 62.23		CDK2_HUMAN (20-308): 5.17e-152: 434: 36.95
+	Hs
		625579 TCPH_HUMAN (4-556): 0: 555: 31.78		CDK2_HUMAN (20-308): 5.17e-152: 434: 36.95
+	Rn
		600476 TCPD_RAT (18-545): 0: 582: 31.22		MK03_RAT (14-351): 2.43e-137: 400: 45.98
+	Rn
		600467 TCPG_RAT (4-555): 0: 578: 29.35		MK03_RAT (14-351): 2.43e-137: 400: 45.98
+	Hs
		173861 TCPG_HUMAN (4-555): 0: 575: 29.53		MK13_HUMAN (1-352): 3.3e-137: 399: 43.98
+	Rn
		600336 TCPA_RAT (9-556): 0: 564: 62.04		MK03_RAT (14-351): 2.43e-137: 400: 45.98
+	Hs
		625220 TCPE_HUMAN (17-552): 0: 530: 29.31		CDK2_HUMAN (20-308): 5.17e-152: 434: 36.95
+	Hs
		173858 TCPE_HUMAN (17-552): 0: 530: 29.31		MK13_HUMAN (1-352): 3.3e-137: 399: 43.98
+	Rn
		600431 TCPB_RAT (16-557): 9.31e-75: 248: 32.61		MK03_RAT (14-351): 2.43e-137: 400: 45.98