HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	25670202, 9927733
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	c-SKI_SMAD_bind~c-SKI_SMAD_bind, Ski_Sno~Ski_Sno
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001843 - neural tube closure and 45 others more... GO:0002089 - lens morphogenesis in camera-type eye GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0008270 - zinc ion binding GO:0008285 - negative regulation of cell population proliferation GO:0009948 - anterior/posterior axis specification GO:0010626 - negative regulation of Schwann cell proliferation GO:0014902 - myotube differentiation GO:0016604 - nuclear body GO:0016605 - PML body GO:0017053 - transcription repressor complex GO:0019901 - protein kinase binding GO:0019904 - protein domain specific binding GO:0021772 - olfactory bulb development GO:0022011 - myelination in peripheral nervous system GO:0030177 - positive regulation of Wnt signaling pathway GO:0030326 - embryonic limb morphogenesis GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway GO:0030514 - negative regulation of BMP signaling pathway GO:0031625 - ubiquitin protein ligase binding GO:0032926 - negative regulation of activin receptor signaling pathway GO:0032991 - protein-containing complex GO:0035019 - somatic stem cell population maintenance GO:0043010 - camera-type eye development GO:0043388 - positive regulation of DNA binding GO:0043585 - nose morphogenesis GO:0045668 - negative regulation of osteoblast differentiation GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046332 - SMAD binding GO:0046811 - histone deacetylase inhibitor activity GO:0048147 - negative regulation of fibroblast proliferation GO:0048593 - camera-type eye morphogenesis GO:0048741 - skeletal muscle fiber development GO:0048870 - cell motility GO:0060021 - roof of mouth development GO:0060038 - cardiac muscle cell proliferation GO:0060041 - retina development in camera-type eye GO:0060325 - face morphogenesis GO:0060349 - bone morphogenesis GO:0060392 - negative regulation of SMAD protein signal transduction GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	2