HitPredict

Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: CSRP1 (P21291)
Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141)
Gene: CSRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10926853
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0030018 - Z disc GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 892 Hs			1 193
+	Hs
		254383 ACTN1_HUMAN (1-892): 0: 697: 100.00		LDB3_HUMAN (7-126): 1.19e-25: 105: 13.93
+	Hs
		521623 ACTN1_HUMAN (1-892): 0: 697: 100.00		PDLI7_HUMAN (68-190): 3.94e-26: 105: 16.54
+	Mm
		1186636 ACTN1_MOUSE (1-892): 0: 694: 99.22		PDLI5_MOUSE (7-126): 2.05e-23: 98.6: 17.50
+	Hs
		211672 ACTN4_HUMAN (11-892): 0: 642: 86.74		PDLI7_HUMAN (68-190): 3.94e-26: 105: 16.54
+	Mm
		1337461 ACTN2_MOUSE (10-892): 0: 643: 80.63		LDB3_MOUSE (7-126): 5.24e-25: 103: 14.75
+	Hs
		254385 ACTN2_HUMAN (10-892): 0: 640: 80.29		LDB3_HUMAN (7-126): 1.19e-25: 105: 13.93
+	Hs
		725704 ACTN2_HUMAN (10-892): 0: 640: 80.29		PDLI7_HUMAN (68-190): 3.94e-26: 105: 16.54
+	Hs
		211687 ACTN4_HUMAN (11-892): 0: 642: 86.74		LIMA1_HUMAN (3-117): 9.06e-21: 91: 27.83
+	Dm
		574811 ACTN_DROME (2-892): 0: 641: 67.39		MLP2_DROME (2-82): 2.7e-14: 72.1: 45.12
+	Dm
		54833 ACTN_DROME (2-892): 0: 641: 67.39		ZASP_DROME (6-64): 9.32e-13: 67.8: 20.34
+	Hs
		725632 ACTN2_HUMAN (10-892): 0: 640: 80.29		CSRP3_HUMAN (115-192): 1.49e-12: 65.1: 50.00
+	Ce
		107755 Q23158_CAEEL (359-891): 1.67e-13: 77: 13.14		G5EFL5_CAEEL (67-193): 3.85e-27: 109: 15.71
+	Hs
		963432 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		PDLI7_HUMAN (68-190): 3.94e-26: 105: 16.54
+	Ce
		107555 H2L2C8_CAEEL (359-891): 1.92e-13: 76.6: 13.31		G5EFG1_CAEEL (67-193): 3.21e-22: 95.1: 15.00
+	Hs
		963448 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		LIMA1_HUMAN (3-117): 9.06e-21: 91: 27.83
+	Hs
		506846 SPTB1_HUMAN (235-847): 3.12e-09: 63.1: 10.29		PDLI7_HUMAN (68-190): 3.94e-26: 105: 16.54
+	Mm
		513820 DMD_MOUSE (399-699): 1.61e-09: 64.3: 17.86		LDB3_MOUSE (7-126): 5.24e-25: 103: 14.75
+	Hs
		963358 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		MICA3_HUMAN (3-118): 4.43e-18: 83.3: 27.94
+	Ce
		104744 G5EC35_CAEEL (152-832): 4.51e-10: 66.1: 11.47		G5EFG1_CAEEL (67-193): 3.21e-22: 95.1: 15.00