HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.997

The method score is based on:

Property Details
Experiments 17909039, 11712088, 7954478, 27684187, 15023525, 19223551, 12830000, 12640114, 31286874, 10772923, 11113628, 12169098, 33961781, 10381631, 18593907, 35271311, 12060769, 17220478, 16125672, 22158051 and 43 others

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Identification Methods affinity chromatography technology, proximity labelling technology, x-ray crystallography, pull down, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~CADH_Y-type_LIR
Common GO terms GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0009410 - response to xenobiotic stimulus
GO:0016020 - membrane
GO:0016328 - lateral plasma membrane
and 11 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 882
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024