Protein: CC137
Coiled-coil domain-containing protein 137

Gene: CC137, CCDC137
Organism: Homo sapiens
Interactions: 207
UniProt ID: Q6PK04

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

447128

NPM
Nucleophosmin

4

1

High-throughput

0.699

High

649340

H1T
Histone H1t

3

2

High-throughput

0.662

High

898698

RL14
Large ribosomal subunit protein eL14

3

0

High-throughput

0.638

High

986082

RL8
Large ribosomal subunit protein uL2

3

0

High-throughput

0.638

High

1245519

NOL12
Nucleolar protein 12

3

0

High-throughput

0.638

High

208288

RRP8
Ribosomal RNA-processing protein 8

3

0

High-throughput

0.634

High

841387

RBM34
RNA-binding protein 34

3

0

High-throughput

0.634

High

1006484

SRPK2
SRSF protein kinase 2

2

1

High-throughput

0.628

High

1245527

SRPK3
SRSF protein kinase 3

2

1

High-throughput

0.628

High

979011

RS6
Small ribosomal subunit protein eS6

3

0

High-throughput

0.628

High

182319

WDR46
WD repeat-containing protein 46

2

3

High-throughput

0.611

High

859327

RL5
Large ribosomal subunit protein uL18

2

0

High-throughput

0.602

High

961757

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.602

High

972457

RS14
Small ribosomal subunit protein uS11

2

0

High-throughput

0.602

High

984442

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.602

High

1245470

DGCR8
Microprocessor complex subunit DGCR8

2

0

High-throughput

0.602

High

1245513

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.602

High

1008773

RED1
Double-stranded RNA-specific editase 1

2

1

High-throughput

0.601

High

472829

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

0

High-throughput

0.585

High

984822

RL31
Large ribosomal subunit protein eL31

2

0

High-throughput

0.585

High

96700

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

428821

RLA0
Large ribosomal subunit protein uL10

2

0

High-throughput

0.576

High

788689

SRP14
Signal recognition particle 14 kDa protein

2

0

High-throughput

0.576

High

1037530

RL18A
Large ribosomal subunit protein eL20

2

0

High-throughput

0.576

High

1245493

REXO4
RNA exonuclease 4

2

0

High-throughput

0.576

High

1245526

RL26L
Ribosomal protein uL24-like

2

1

High-throughput

0.571

High

1245518

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

1149915

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.549

High

396350

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

810170

RL3
Large ribosomal subunit protein uL3

2

0

High-throughput

0.547

High

255924

Z354A
Zinc finger protein 354A

1

3

High-throughput

0.536

High

287026

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

3

High-throughput

0.536

High

288677

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.536

High

301089

RL1D1
Ribosomal L1 domain-containing protein 1

1

1

High-throughput

0.536

High

345962

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.536

High

476726

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.536

High

521758

H14
Histone H1.4

1

2

High-throughput

0.536

High

600178

ZNF22
Zinc finger protein 22

1

1

High-throughput

0.536

High

600321

ZNF24
Zinc finger protein 24

1

5

High-throughput

0.536

High

833129

MNDA
Myeloid cell nuclear differentiation antigen

1

1

High-throughput

0.536

High

977025

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

1

High-throughput

0.536

High

985215

RL10A
Large ribosomal subunit protein uL1

1

1

High-throughput

0.536

High

1027534

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

1029316

SET
Protein SET

1

1

High-throughput

0.536

High

1037219

H11
Histone H1.1

1

2

High-throughput

0.536

High

1044425

ZNF92
Zinc finger protein 92

1

2

High-throughput

0.536

High

1061023

SRSF1
Serine/arginine-rich splicing factor 1

1

2

High-throughput

0.536

High

1099124

SRSF5
Serine/arginine-rich splicing factor 5

1

2

High-throughput

0.536

High

1099399

SRSF6
Serine/arginine-rich splicing factor 6

1

4

High-throughput

0.536

High

1219017

RSBN1
Lysine-specific demethylase 9

1

1

High-throughput

0.536

High

1234770

ZN770
Zinc finger protein 770

1

3

High-throughput

0.536

High

1243563

RSBNL
Lysine-specific demethylase RSBN1L

1

1

High-throughput

0.536

High

1245456

ZN467
Zinc finger protein 467

1

3

High-throughput

0.536

High

1245462

ZCHC7
Zinc finger CCHC domain-containing protein 7

1

2

High-throughput

0.536

High

1245465

BRX1
Ribosome biogenesis protein BRX1 homolog

1

2

High-throughput

0.536

High

1245467

ZN483
Zinc finger protein 483

1

4

High-throughput

0.536

High

1245468

NOC3L
Nucleolar complex protein 3 homolog

1

1

High-throughput

0.536

High

1245479

ZN845
Zinc finger protein 845

1

2

High-throughput

0.536

High

1245480

ZN668
Zinc finger protein 668

1

3

High-throughput

0.536

High

1245482

ZN512
Zinc finger protein 512

1

4

High-throughput

0.536

High

1245483

ZN317
Zinc finger protein 317

1

3

High-throughput

0.536

High

1245486

ZN184
Zinc finger protein 184

1

2

High-throughput

0.536

High

1245491

ZNF2
Zinc finger protein 2

1

2

High-throughput

0.536

High

1245492

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

1

High-throughput

0.536

High

1245496

TSYL2
Testis-specific Y-encoded-like protein 2

1

1

High-throughput

0.536

High

1245498

ZN768
Zinc finger protein 768

1

2

High-throughput

0.536

High

1245500

YTDC2
3'-5' RNA helicase YTHDC2

1

1

High-throughput

0.536

High

1245504

RPF1
Ribosome production factor 1

1

1

High-throughput

0.536

High

1245505

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.536

High

1245512

DDX56
Probable ATP-dependent RNA helicase DDX56

1

1

High-throughput

0.536

High

1245516

ZN624
Zinc finger protein 624

1

2

High-throughput

0.536

High

1245517

ZBT47
Zinc finger and BTB domain-containing protein 47

1

4

High-throughput

0.536

High

1245528

YBOX2
Y-box-binding protein 2

1

1

High-throughput

0.536

High

137456

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

0

High-throughput

0.513

High

140963

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

188496

NVL
Nuclear valosin-containing protein-like

1

0

High-throughput

0.513

High

191681

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.513

High

250669

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

290604

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.513

High

338139

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.513

High

355542

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

High-throughput

0.513

High

443075

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.513

High

502394

H2A1
Histone H2A type 1

1

0

High-throughput

0.513

High

586753

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

615837

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

686219

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

785236

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

809685

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

824198

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

842409

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

854120

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

855113

NOP2
28S rRNA

1

0

High-throughput

0.513

High

860246

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

860804

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

969273

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

969925

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

973475

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

975759

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

978577

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

985486

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.513

High

985722

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

1016062

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1043694

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.513

High

1087427

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.513

High

1109150

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

1112056

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.513

High

1128033

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.513

High

1130307

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.513

High

1130761

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.513

High

1139939

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.513

High

1146509

TTF1
Transcription termination factor 1

1

0

High-throughput

0.513

High

1148111

PUM3
Pumilio homolog 3

1

0

High-throughput

0.513

High

1150295

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.513

High

1150334

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

1

0

High-throughput

0.513

High

1151141

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

1178050

RN151
RING finger protein 151

1

0

High-throughput

0.513

High

1210459

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.513

High

1219398

TUT7
Terminal uridylyltransferase 7

1

0

High-throughput

0.513

High

1228587

SPT2
Protein SPT2 homolog

1

0

High-throughput

0.513

High

1231619

RL7L
Ribosomal protein uL30-like

1

0

High-throughput

0.513

High

1245453

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.513

High

1245454

NOL8
Nucleolar protein 8

1

0

High-throughput

0.513

High

1245455

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.513

High

1245459

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.513

High

1245461

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.513

High

1245474

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1245475

DDX27
Probable ATP-dependent RNA helicase DDX27

1

0

High-throughput

0.513

High

1245476

CENPN
Centromere protein N

1

0

High-throughput

0.513

High

1245481

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

1245484

UIF
UAP56-interacting factor

1

0

High-throughput

0.513

High

1245487

EBP2
Probable rRNA-processing protein EBP2

1

0

High-throughput

0.513

High

1245488

RBM4B
RNA-binding protein 4B

1

0

High-throughput

0.513

High

1245489

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.513

High

1245490

BUD13
BUD13 homolog

1

0

High-throughput

0.513

High

1245494

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

1245499

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.513

High

1245501

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.513

High

1245503

DDX31
ATP-dependent DNA helicase DDX31

1

0

High-throughput

0.513

High

1245507

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.513

High

1245508

SDA1
Protein SDA1 homolog

1

0

High-throughput

0.513

High

1245510

RBM28
RNA-binding protein 28

1

0

High-throughput

0.513

High

1245511

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

1245520

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

1245521

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

1245522

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

1245524

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

1245531

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.513

High

1245532

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

315700

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

372345

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406299

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

960147

RL26
Large ribosomal subunit protein uL24

1

1

High-throughput

0.479

High

1161498

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1207403

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1245463

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1245471

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

1245472

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

1245485

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

1245509

NLE1
Notchless protein homolog 1

1

1

High-throughput

0.479

High

1245525

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.479

High

129194

MEN1
Menin

1

0

High-throughput

0.458

High

132108

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

223133

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

242036

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

693801

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

768469

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

830940

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

937790

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

982708

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

1088404

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.458

High

1137785

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1138327

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1245457

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1245460

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1245466

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1245473

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

1245477

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1245506

RC3H2
Roquin-2

1

0

High-throughput

0.458

High

1245515

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1245530

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

47536

RPSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.445

High

72786

B0UZZ8
WD repeat-containing protein 46

1

3

High-throughput

0.445

High

213414

ZSC12
Zinc finger and SCAN domain-containing protein 12

1

4

High-throughput

0.445

High

1212336

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

1245514

H2AW
Core histone macro-H2A.2

1

1

High-throughput

0.445

High

1245523

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

601736

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.426

High

1245478

ZN414
Zinc finger protein 414

1

0

High-throughput

0.426

High

1245529

RBMX2
RNA-binding motif protein, X-linked 2

1

0

High-throughput

0.426

High

69953

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

1245458

ARHGJ
Rho guanine nucleotide exchange factor 19

2

0

High-throughput

0.298

High

939796

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

High-throughput

0.282

High

1103512

MPP3
MAGUK p55 subfamily member 3

1

0

High-throughput

0.282

High

354020

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

608293

EGLN
Endoglin

1

0

High-throughput

0.279

Low

1127409

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1245464

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.279

Low

1245469

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.279

Low

1245495

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.279

Low

1245502

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.279

Low

348147

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

0

High-throughput

0.249

Low

610009

VGFR1
Vascular endothelial growth factor receptor 1

1

0

High-throughput

0.249

Low

931954

EPHB4
Ephrin type-B receptor 4

1

0

High-throughput

0.249

Low

1126109

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1245452

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1245497

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

568911

SC5A1
Sodium/glucose cotransporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025