HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	25468996, 34591612, 28877994, 19041755
Identification Methods	proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030054 - cell junction GO:0044331 - cell-cell adhesion mediated by cadherin GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 1121
+	Hs
		522201 CADH1_HUMAN (1-882): 0: 836: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		522282 CADH1_HUMAN (1-882): 0: 836: 100.00		PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16
+	Hs
		521831 CADH1_HUMAN (1-882): 0: 836: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		522229 CADH1_HUMAN (1-882): 0: 836: 100.00		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		580262 CADH2_HUMAN (28-881): 0: 769: 45.86		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		606310 CADH3_HUMAN (3-882): 0: 716: 53.06		SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18
+	Hs
		876362 DSC2_HUMAN (33-874): 0: 652: 27.88		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		877564 CAD13_HUMAN (8-701): 0: 633: 36.20		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Hs
		1231374 PCDA4_HUMAN (377-862): 2.83e-62: 229: 16.14		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32