HitPredict

Interactor 1: PSA1 (P12881)
Proteasome subunit alpha type-1 (PROS-Dm35) (Proteasome 35 kDa subunit)
Gene: Prosalpha6

Interactor 2: PSMD1 (Q9V3P6)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory complex subunit p110) (26S proteasome regulatory subunit RPN2)
Gene: Rpn2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 279 Dm			1 1020
+	Dm
		611652 PSA71_DROME (4-236): 4.09e-102: 299: 30.93		PSMD1_DROME (1-1004): 0: 1198: 100.00
+	Hs
		637529 PSA1_HUMAN (1-269): 8.96e-103: 302: 52.42		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Dm
		1278636 PSA5_DROME (1-240): 3.68e-93: 276: 28.11		PSMD1_DROME (1-1004): 0: 1198: 100.00
+	Hs
		656297 PSA5_HUMAN (1-239): 7.88e-95: 280: 30.08		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		156342 PSA7_HUMAN (6-237): 5.84e-94: 279: 37.02		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		893734 PSA6_HUMAN (1-243): 1.35e-92: 275: 29.48		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Hs
		685 PSA1_HUMAN (1-269): 8.96e-103: 302: 52.42		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Hs
		689 PSA5_HUMAN (1-239): 7.88e-95: 280: 30.08		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Hs
		699 PSA6_HUMAN (1-243): 1.35e-92: 275: 29.48		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Hs
		688 PSA4_HUMAN (1-236): 2.86e-90: 270: 29.22		A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50
+	Hs
		637407 PSA1_HUMAN (1-269): 8.96e-103: 302: 52.42		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		656214 PSA5_HUMAN (1-239): 7.88e-95: 280: 30.08		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		156281 PSA7_HUMAN (6-237): 5.84e-94: 279: 37.02		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		893662 PSA6_HUMAN (1-243): 1.35e-92: 275: 29.48		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Hs
		638122 PSA4_HUMAN (1-236): 2.86e-90: 270: 29.22		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Dm
		522523 PSA1_DROME (1-279): 9.24e-111: 322: 100.00		Q9VW54_DROME (13-812): 0: 617: 17.03
+	Dm
		611672 PSA71_DROME (4-236): 4.09e-102: 299: 30.93		Q9VW54_DROME (13-812): 0: 617: 17.03
+	Dm
		1278652 PSA5_DROME (1-240): 3.68e-93: 276: 28.11		Q9VW54_DROME (13-812): 0: 617: 17.03
+	Sp
		953217 PSA5_SCHPO (1-242): 1.8e-94: 280: 32.40		RPN1_SCHPO (9-810): 0: 574: 16.86
+	Sp
		145196 PSA6_SCHPO (1-266): 3.63e-93: 277: 46.99		RPN1_SCHPO (9-810): 0: 574: 16.86