Protein: LSG1
Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-)

Gene: LSG1
Organism: Homo sapiens
Interactions: 158
UniProt ID: Q9H089

Gene Ontology (top 5):
GO:0000054 - ribosomal subunit export from nucleus
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1327320

VAPA
Vesicle-associated membrane protein-associated protein A

4

1

High-throughput

0.704

High

310800

VAPB
Vesicle-associated membrane protein-associated protein B/C

4

1

High-throughput

0.699

High

1327329

DRG1
Developmentally-regulated GTP-binding protein 1

1

6

High-throughput

0.691

High

360393

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

4

High-throughput

0.640

High

1064703

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.618

High

996512

FGL1
Fibrinogen-like protein 1

3

1

High-throughput

0.609

High

1252828

PLPR1
Phospholipid phosphatase-related protein type 1

2

0

High-throughput

0.585

High

347849

MYC
Myc proto-oncogene protein

2

7

High-throughput

0.584

High

370397

ESR1
Estrogen receptor

2

10

High-throughput

0.571

High

1284056

LRC59
Leucine-rich repeat-containing protein 59

2

0

High-throughput

0.559

High

133660

NOP56
Nucleolar protein 56

1

7

High-throughput

0.536

High

283599

SRP72
Signal recognition particle subunit SRP72

1

4

High-throughput

0.536

High

387475

P53
Cellular tumor antigen p53

1

3

High-throughput

0.536

High

447998

SRP19
Signal recognition particle 19 kDa protein

1

2

High-throughput

0.536

High

509116

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

643399

HMGB2
High mobility group protein B2

1

7

High-throughput

0.536

High

649727

RL10
Large ribosomal subunit protein uL16

1

5

High-throughput

0.536

High

736718

RL4
Large ribosomal subunit protein uL4

1

9

High-throughput

0.536

High

806166

RL5
Large ribosomal subunit protein uL18

1

5

High-throughput

0.536

High

828898

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.536

High

841006

MAP2
Methionine aminopeptidase 2

1

5

High-throughput

0.536

High

908142

RS16
Small ribosomal subunit protein uS9

1

4

High-throughput

0.536

High

923208

RL11
Large ribosomal subunit protein uL5

1

7

High-throughput

0.536

High

951751

RL19
Large ribosomal subunit protein eL19

1

5

High-throughput

0.536

High

1263530

PSPC1
Paraspeckle component 1

1

5

High-throughput

0.536

High

1327314

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.536

High

1327326

SRP68
Signal recognition particle subunit SRP68

1

2

High-throughput

0.536

High

204050

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

532609

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.513

High

887608

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1327319

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.513

High

409226

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.493

High

48495

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

120629

RHOD
Rho-related GTP-binding protein RhoD

1

9

High-throughput

0.479

High

122990

MEN1
Menin

1

2

High-throughput

0.479

High

163972

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

177998

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.479

High

228635

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

273979

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

323112

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

14

High-throughput

0.479

High

374847

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

391165

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

436496

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

442482

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

456933

FURIN
Furin

1

1

High-throughput

0.479

High

508187

FGFR1
Fibroblast growth factor receptor 1

1

8

High-throughput

0.479

High

592482

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

595401

LMNB1
Lamin-B1

1

4

High-throughput

0.479

High

603702

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

654753

CALX
Calnexin

1

1

High-throughput

0.479

High

835518

GSK3A
Glycogen synthase kinase-3 alpha

1

2

High-throughput

0.479

High

835983

GSK3B
Glycogen synthase kinase-3 beta

1

3

High-throughput

0.479

High

881020

IF6
Eukaryotic translation initiation factor 6

1

5

High-throughput

0.479

High

890403

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

900879

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

909095

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

918671

H2B1C
Histone H2B type 1-C/E/F/G/I

1

6

High-throughput

0.479

High

951317

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

982475

1433F
14-3-3 protein eta

1

1

High-throughput

0.479

High

990662

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

999073

EP300
Histone acetyltransferase p300

1

7

High-throughput

0.479

High

1017784

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

1036061

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1053175

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.479

High

1064125

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

1153920

IFIX
Pyrin and HIN domain-containing protein 1

1

5

High-throughput

0.479

High

1162116

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.479

High

1167896

DJC14
DnaJ homolog subfamily C member 14

1

2

High-throughput

0.479

High

1200648

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1220653

MIRO2
Mitochondrial Rho GTPase 2

1

9

High-throughput

0.479

High

1236487

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.479

High

1243386

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.479

High

1256043

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.479

High

1256385

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1269566

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

1282215

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

2

High-throughput

0.479

High

1287988

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

1293985

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

1296062

DNJC1
DnaJ homolog subfamily C member 1

1

12

High-throughput

0.479

High

1300775

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1304419

DNJC2
DnaJ homolog subfamily C member 2

1

5

High-throughput

0.479

High

1311386

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1327310

SP110
Sp110 nuclear body protein

1

9

High-throughput

0.479

High

1327311

ANLN
Anillin

1

3

High-throughput

0.479

High

1327317

TBA8
Tubulin alpha-8 chain

1

1

High-throughput

0.479

High

1327324

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1327325

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.479

High

1327327

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1327334

RBM8A
RNA-binding protein 8A

1

3

High-throughput

0.479

High

1327304

DJC25
DnaJ homolog subfamily C member 25

1

7

High-throughput

0.470

High

155442

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

168277

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.458

High

390512

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

573895

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

786118

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

795271

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

825536

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

839117

EMD
Emerin

1

0

High-throughput

0.458

High

845719

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.458

High

847647

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

940555

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

941415

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

961817

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.458

High

1040246

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1198680

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

0

High-throughput

0.458

High

1218506

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1237469

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1237785

ARL10
ADP-ribosylation factor-like protein 10

1

0

High-throughput

0.458

High

1240289

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1303552

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1313045

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1319235

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1327305

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.458

High

1327308

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1327309

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1327312

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1327313

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1327316

S39A1
Zinc transporter ZIP1

1

0

High-throughput

0.458

High

1327318

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1327321

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1327323

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1327331

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1327332

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

402457

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

989110

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.445

High

995586

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.445

High

1059363

CASP8
Caspase-8

1

1

High-throughput

0.445

High

178766

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

385491

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

665523

EPHA8
Ephrin type-A receptor 8

1

3

High-throughput

0.437

High

959664

VIGLN
Vigilin

1

4

High-throughput

0.437

High

968476

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

7

High-throughput

0.437

High

1081597

NTRK3
NT-3 growth factor receptor

1

7

High-throughput

0.437

High

1171635

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1188838

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

1198164

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.437

High

1263901

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1297247

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

5

High-throughput

0.437

High

1327307

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1327315

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1327322

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

4

High-throughput

0.437

High

1327328

ALK
ALK tyrosine kinase receptor

1

6

High-throughput

0.437

High

1327330

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.437

High

1327333

MAFB
Transcription factor MafB

1

4

High-throughput

0.437

High

1327335

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.437

High

1238850

TTC29
Tetratricopeptide repeat protein 29

2

0

High-throughput

0.318

High

159676

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

650147

CO8A1
Collagen alpha-1(VIII) chain

1

0

High-throughput

0.279

Low

1118285

GAG2E
G antigen 2E

1

0

High-throughput

0.279

Low

1138422

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1231413

CT197
Putative uncharacterized protein encoded by LINC02910

1

0

High-throughput

0.279

Low

1302831

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1327336

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

451090

SPRC
SPARC

1

0

High-throughput

0.269

Low

1072820

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

1230362

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1283937

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1327306

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024