HitPredict

Interactor 1: MYH1 (P12882)
Myosin-1 (Myosin heavy chain 1) (Myosin heavy chain 2x) (MyHC-2x) (Myosin heavy chain IIx/d) (MyHC-IIx/d) (Myosin heavy chain, skeletal muscle, adult 1)
Gene: MYH1

Interactor 2: KAPCB (P22694)
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)
Gene: PRKACB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1939 Hs			1 351
+	Hs
		610802 MYH4_HUMAN (1-1939): 0: 1166: 94.07		KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00
+	Hs
		610795 MYH2_HUMAN (1-1939): 0: 1150: 94.38		KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00
+	Hs
		528359 MYH6_HUMAN (3-1934): 0: 1140: 80.59		KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00
+	Hs
		116964 MYH1_HUMAN (1-1939): 0: 1170: 100.00		SGK1_HUMAN (1-348): 5.91e-143: 413: 37.71
+	Mm
		554901 MYH6_MOUSE (3-1934): 0: 1135: 80.69		KPCE_MOUSE (9-351): 1.24e-139: 415: 35.85
+	Hs
		568568 MYH10_HUMAN (1083-1938): 2.16e-54: 212: 15.35		KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88
+	Hs
		568567 MYH9_HUMAN (1104-1938): 6.77e-54: 211: 16.02		KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88
+	Mm
		554927 MYH7_MOUSE (960-1939): 6.33e-61: 234: 17.17		KPCE_MOUSE (9-351): 1.24e-139: 415: 35.85
+	Dm
		397193 MYSN_DROME (860-1938): 3.08e-58: 225: 16.91		KPC1_DROME (9-351): 4.59e-141: 417: 36.16
+	Hs
		681696 MYH9_HUMAN (1104-1938): 6.77e-54: 211: 16.02		AKT1_HUMAN (2-347): 4.4e-147: 425: 39.03
+	Hs
		724784 MYH9_HUMAN (1104-1938): 6.77e-54: 211: 16.02		KPCE_HUMAN (3-351): 3.98e-140: 416: 34.25
+	Hs
		117013 MYH14_HUMAN (1418-1939): 4.82e-28: 126: 15.71		SGK1_HUMAN (1-348): 5.91e-143: 413: 37.71