Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: PHAG1 (Q9NWQ8)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp)
Gene: PAG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 21746865, 18070987
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAG~SH2
Common GO terms GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0035556 - intracellular signal transduction
GO:0042169 - SH2 domain binding
GO:0045121 - membrane raft
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 536
Hs

1 432
+ Mm
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+ Hs
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+ Rn

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Last updated: 15 Jul 2024