HitPredict

Interactor 1: NAT1 (P12945)
N-terminal acetyltransferase A complex subunit NAT1 (NatA complex subunit NAT1) (Amino-terminal, alpha-amino, acetyltransferase 1)
Gene: NAT1

Interactor 2: NAT5 (Q08689)
N-alpha-acetyltransferase NAT5 (NatA complex subunit NAT5) (EC 2.3.1.258)
Gene: NAT5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	14517307, 16554755, 37968396
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Acetyltransf_1~NatA_aux_su
Common GO terms	GO:0006474 - N-terminal protein amino acid acetylation GO:0031415 - NatA complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 854 Sc			1 176
+	Sc
		427336 NAT1_YEAST (1-854): 0: 607: 100.00		ARD1_YEAST (6-175): 4.67e-43: 144: 12.25
+	Hs
		1154519 NAA16_HUMAN (15-825): 1.04e-142: 445: 28.28		NAA11_HUMAN (7-176): 7.68e-52: 167: 14.62
+	Hs
		782253 NAA16_HUMAN (15-825): 1.04e-142: 445: 28.28		NAA10_HUMAN (7-176): 5.49e-52: 167: 14.04
+	Hs
		1154521 NAA16_HUMAN (15-825): 1.04e-142: 445: 28.28		NAA50_HUMAN (1-175): 2.4e-44: 146: 22.73
+	Dm
		1373874 Q9VWI2_DROME (10-794): 2.33e-127: 405: 28.36		Q9VT75_DROME (7-176): 3.53e-50: 161: 15.21
+	Dm
		1342125 Q9VWI2_DROME (10-794): 2.33e-127: 405: 28.36		SAN_DROME (1-175): 1.11e-42: 142: 21.59
+	Hs
		901294 NAA25_HUMAN (24-631): 6.74e-62: 228: 12.33		NAA20_HUMAN (5-176): 4.09e-49: 158: 13.22
+	Dm
		116294 NAA25_DROME (24-616): 2.37e-53: 202: 12.78		M9PI14_DROME (5-176): 2.75e-49: 159: 16.86
+	Ce
		1094552 NAA25_CAEEL (24-607): 6.17e-44: 173: 13.65		Q965S3_CAEEL (5-176): 2.38e-43: 143: 12.79
+	Hs
		1311627 NAA15_HUMAN (1-330): 3.04e-09: 62.9: 12.46		NAA11_HUMAN (7-176): 7.68e-52: 167: 14.62
+	Hs
		782289 NAA15_HUMAN (1-330): 3.04e-09: 62.9: 12.46		NAA10_HUMAN (7-176): 5.49e-52: 167: 14.04
+	Mm
		102622 G3X8Y3_MOUSE (1-330): 3.48e-09: 62.6: 12.46		NAA10_MOUSE (7-176): 3.09e-51: 165: 14.04
+	Hs
		183162 KDM6A_HUMAN (177-530): 5.48e-24: 111: 9.97		CSR2B_HUMAN (11-172): 8.23e-25: 102: 12.73
+	Hs
		1315323 NAA15_HUMAN (1-330): 3.04e-09: 62.9: 12.46		NAA50_HUMAN (1-175): 2.4e-44: 146: 22.73
+	Sp
		251650 NAT1_SCHPO (4-464): 1.42e-10: 67.2: 10.81		YCPD_SCHPO (5-175): 2.04e-25: 97.1: 26.16