HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26641092, 30585729
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 475
+	Hs
		523768 XRCC6_HUMAN (1-609): 0: 666: 100.00		SART3_HUMAN (10-377): 4.33e-86: 285: 22.52
+	Hs
		523749 XRCC6_HUMAN (1-609): 0: 666: 100.00		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		524925 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16