HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27545878
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 1072
+	Hs
		525014 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		523595 XRCC6_HUMAN (1-609): 0: 666: 100.00		NU153_HUMAN (89-504): 1.97e-28: 126: 13.40
+	Hs
		524059 XRCC6_HUMAN (1-609): 0: 666: 100.00		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		525094 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44