Protein: MLH2
DNA mismatch repair protein MLH2 (MutL protein homolog 2)

Gene: MLH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 22
UniProt ID: Q07980

Gene Ontology (top 5):
GO:0000710 - meiotic mismatch repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006298 - mismatch repair
GO:0007131 - reciprocal meiotic recombination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

807646

MLH1
DNA mismatch repair protein MLH1

8

14

Small-scale

0.969

High

546512

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.712

High

527839

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.691

High

909506

HFM1
ATP-dependent DNA helicase MER3

3

3

Small-scale

0.669

High

672031

MSH3
DNA mismatch repair protein MSH3

1

20

Small-scale

0.647

High

682945

MSH2
DNA mismatch repair protein MSH2

1

20

Small-scale

0.647

High

1044186

MSH6
DNA mismatch repair protein MSH6

1

20

Small-scale

0.647

High

571283

PMS1
DNA mismatch repair protein PMS1

1

14

Small-scale

0.621

High

525343

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.575

High

742532

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.575

High

804508

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.575

High

819958

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.575

High

916487

SUT1
Sterol uptake protein 1

1

0

High-throughput

0.518

High

1061396

ARP7
Actin-related protein 7

1

3

High-throughput

0.515

High

557780

SRS2
ATP-dependent DNA helicase SRS2

1

1

Small-scale

0.481

High

676409

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

584942

TRM1
tRNA

1

0

High-throughput

0.438

High

826506

DJP1
DnaJ-like protein 1

1

2

High-throughput

0.407

High

1061395

RPN8
26S proteasome regulatory subunit RPN8

2

0

High-throughput

0.324

High

805270

SBE22
Protein SBE22

1

0

High-throughput

0.249

Low

394952

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

577230

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025