HitPredict

Interactor 1: LYL1 (P12980)
Protein lyl-1 (Class A basic helix-loop-helix protein 18) (bHLHa18) (Lymphoblastic leukemia-derived sequence 1)
Gene: LYL1

Interactor 2: RBTN1 (P25800)
Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1)
Gene: LMO1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	7957052
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 280 Hs			1 156
+	Hs
		524537 LYL1_HUMAN (1-280): 1e-53: 177: 100.00		RBTN2_HUMAN (7-149): 3.37e-46: 149: 54.17
+	Hs
		568179 TAL1_HUMAN (51-267): 1.7e-34: 128: 40.83		RBTN2_HUMAN (7-149): 3.37e-46: 149: 54.17
+	Hs
		1148470 FIGLA_HUMAN (96-280): 1.36e-29: 113: 26.04		LHX8_HUMAN (14-143): 5.2e-48: 160: 40.00
+	Mm
		603898 TAL1_MOUSE (55-219): 1.79e-32: 123: 45.78		RBTN2_MOUSE (7-149): 2.92e-46: 149: 54.17
+	Hs
		568180 TAL1_HUMAN (51-267): 1.7e-34: 128: 40.83		RBTN1_HUMAN (1-156): 1.87e-43: 142: 100.00
+	Dm
		114761 Q9VHG3_DROME (26-234): 1.6e-32: 122: 21.10		M9PD53_DROME (2-151): 1.52e-40: 144: 32.28
+	Mm
		604035 TAL1_MOUSE (55-219): 1.79e-32: 123: 45.78		LMO3_MOUSE (12-156): 1.9e-40: 134: 89.66
+	Hs
		638295 TAL2_HUMAN (149-215): 7.25e-27: 102: 67.16		RBTN2_HUMAN (7-149): 3.37e-46: 149: 54.17
+	Mm
		1143747 TAL2_MOUSE (149-237): 1.4e-27: 104: 53.85		RBTN1_MOUSE (1-156): 2.41e-43: 142: 98.72
+	Hs
		638508 TAL2_HUMAN (149-215): 7.25e-27: 102: 67.16		RBTN1_HUMAN (1-156): 1.87e-43: 142: 100.00
+	Dm
		1368265 Q9W4I4_DROME (148-208): 3.36e-25: 100: 50.82		Q9VJ00_DROME (2-151): 2.13e-40: 143: 32.28
+	Mm
		1143746 TAL2_MOUSE (149-237): 1.4e-27: 104: 53.85		LMO3_MOUSE (12-156): 1.9e-40: 134: 89.66
+	Hs
		210862 TCF21_HUMAN (130-209): 1.64e-27: 106: 39.51		LMO4_HUMAN (7-154): 3.11e-39: 132: 47.30
+	Hs
		546094 MYOG_HUMAN (95-279): 5.4e-27: 106: 18.42		LMO3_HUMAN (13-156): 1.16e-38: 130: 89.58
+	Dm
		1359764 Q9VHG3_DROME (26-234): 1.6e-32: 122: 21.10		Q9V472_DROME (4-88): 3.59e-15: 73.4: 23.26
+	Hs
		1163323 FIGLA_HUMAN (96-280): 1.36e-29: 113: 26.04		LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78
+	Dm
		80870 DIMM_DROME (97-249): 3.54e-28: 113: 21.38		APTE_DROME (88-151): 1.91e-10: 59.6: 20.31
+	Hs
		551558 TFE2_HUMAN (18-254): 5.92e-28: 114: 18.60		LMX1A_HUMAN (83-152): 5.44e-09: 55.3: 19.72
+	Hs
		1163324 FIGLA_HUMAN (96-280): 1.36e-29: 113: 26.04		LHX6_HUMAN (6-81): 5.92e-09: 55.4: 22.08
+	Dm
		112565 Q9W4I4_DROME (148-208): 3.36e-25: 100: 50.82		M9NCY1_DROME (4-80): 1.04e-12: 66.1: 20.51