HitPredict

Interactor 1: COX41 (P13073)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)
Gene: COX4I1

Interactor 2: CX7A2 (P14406)
Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL)
Gene: COX7A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29568061, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005751 - mitochondrial respiratory chain complex IV GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen GO:0031966 - mitochondrial membrane GO:0045333 - cellular respiration
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 169 Hs			1 83
+	Hs
		525421 COX41_HUMAN (1-169): 7.24e-92: 266: 100.00		CX7A1_HUMAN (6-81): 7.5e-36: 117: 55.26
+	Hs
		147650 COX41_HUMAN (1-169): 7.24e-92: 266: 100.00		COX7R_HUMAN (25-82): 6.57e-27: 96.3: 58.62
+	Hs
		147665 COX42_HUMAN (1-169): 3.8e-66: 201: 49.71		COX7R_HUMAN (25-82): 6.57e-27: 96.3: 58.62