Protein: PFF1
Vacuolar membrane protease (EC 3.4.-.-) (FXNA-related family protease 1)

Gene: PFF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P38244

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0006508 - proteolysis
GO:0008235 - metalloexopeptidase activity
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

592199

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.479

High

603457

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.479

High

693179

PHO91
Low-affinity phosphate transporter PHO91

1

2

High-throughput

0.479

High

796491

VAC8
Vacuolar protein 8

1

1

High-throughput

0.479

High

796492

VTC1
Vacuolar transporter chaperone complex subunit 1

1

3

High-throughput

0.479

High

796494

SYG1
Protein SYG1

1

1

High-throughput

0.479

High

796496

VTC2
Vacuolar transporter chaperone complex subunit 2

1

5

High-throughput

0.479

High

796497

VTC4
Vacuolar transporter chaperone complex subunit 4

1

5

High-throughput

0.479

High

796502

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

5

High-throughput

0.479

High

796503

YMB8
Uncharacterized vacuolar membrane protein YML018C

1

3

High-throughput

0.479

High

796505

NYV1
Vacuolar v-SNARE NYV1

1

3

High-throughput

0.479

High

547047

PPB
Repressible alkaline phosphatase

1

0

High-throughput

0.458

High

645816

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.458

High

726562

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.458

High

735712

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.458

High

740049

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

High-throughput

0.458

High

743677

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.458

High

796488

VTC5
Vacuole transporter chaperone complex subunit 5

1

0

High-throughput

0.458

High

796489

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.458

High

796490

KC13
Casein kinase I homolog 3

1

0

High-throughput

0.458

High

796495

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.458

High

796499

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

796500

VSB1
Vacuolar basic amino acid transporter VSB1

1

0

High-throughput

0.458

High

796504

VBA4
Vacuolar basic amino acid transporter 4

1

0

High-throughput

0.458

High

523739

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

706915

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

796501

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.417

High

796493

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.407

High

796506

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

796498

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.261

Low

452656

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025