HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22940862, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 945
+	Sc
		523387 HSP71_YEAST (1-639): 0: 968: 97.04		RPN2_YEAST (1-945): 0: 1119: 100.00
+	Hs
		1098010 Q53FC7_HUMAN (4-639): 0: 946: 69.95		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Hs
		537089 HSP7C_HUMAN (2-639): 0: 945: 74.34		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Hs
		930874 HSP72_HUMAN (2-639): 0: 930: 71.23		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Ce
		482122 HSP1_CAEEL (3-639): 0: 932: 75.82		Q9GZH5_CAEEL (9-767): 5.2e-157: 489: 16.65
+	Sc
		523848 HSP71_YEAST (1-639): 0: 968: 97.04		RPN1_YEAST (9-573): 1.14e-134: 430: 17.33
+	Sc
		526617 HSP72_YEAST (1-639): 0: 933: 100.00		RPN1_YEAST (9-573): 1.14e-134: 430: 17.33