Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: TOA1 (P32773)
Transcription initiation factor IIA large subunit (TFIIA large subunit) (TFIIA 32 kDa subunit)
Gene: TOA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 8183347, 8629014, 9447997, 11223526, 12972251, 12527429, 8754846, 8610010, 7862117, 10675336, 15340090, 10082550, 11048951, 9488485, 18981477, 19098311, 2247058
Identification Methods comigration in non denaturing gel electrophoresis, x-ray crystallography, affinity chromatography technology, pull down
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains TBP~TFIIA
Common GO terms GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005672 - transcription factor TFIIA complex
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051123 - RNA polymerase II preinitiation complex assembly
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 240
Sc

1 286
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Mm
+ Hs
+ Ce
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024