Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: NCB1 (P40096)
Negative cofactor 2 complex subunit alpha (NC2 complex subunit alpha) (Transcription repressor BUR6)
Gene: BUR6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 18703679, 9671455, 19098311, 37968396, 9096360
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CBFD_NFYB_HMF~TBP
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051123 - RNA polymerase II preinitiation complex assembly
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 240
Sc

1 142
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024