HitPredict

Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: TAF6 (P53040)
Transcription initiation factor TFIID subunit 6 (TBP-associated factor 6) (TBP-associated factor 60 kDa) (TAFII-60) (TAFII60)
Gene: TAF6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 11805826, 12052880, 10788514, 8340360, 8083216, 7667272, 9844639, 10783167, 8662725, 16429126
Identification Methods tandem affinity purification, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005669 - transcription factor TFIID complex
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 240
Sc

1 516
+ Mm
+ Hs
+ Dm
+ Dm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024