HitPredict

Interactor 1: BMP1 (P13497)
Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
Gene: BMP1

Interactor 2: TLL2 (Q9Y6L7)
Tolloid-like protein 2 (EC 3.4.24.-)
Gene: TLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Astacin~Astacin, CUB~CUB, CUB~EGF_CA, CUB~FXa_inhibition, EGF_CA~EGF_CA, EGF_CA~FXa_inhibition, FXa_inhibition~FXa_inhibition
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 986
Hs

1 1015
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ss
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024