HitPredict

Interactor 1: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Interactor 2: TSG6 (P98066)
Tumor necrosis factor-inducible gene 6 protein (EC 3.1.1.-) (Hyaluronate-binding protein) (TNF-stimulated gene 6 protein) (TSG-6) (Tumor necrosis factor alpha-induced protein 6) (TNF alpha-induced protein 6)
Gene: TNFAIP6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	24501198, 27044744
Identification Methods	surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0006954 - inflammatory response GO:0007267 - cell-cell signaling GO:0030335 - positive regulation of cell migration
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 91 Hs			1 277
+	Hs
		945627 CCL7_HUMAN (17-90): 6.02e-28: 98.8: 28.95		TSG6_HUMAN (12-277): 2.95e-95: 283: 100.00
+	Hs
		528215 CCL2_HUMAN (1-90): 2.17e-27: 97.3: 33.70		TSG6_HUMAN (12-277): 2.95e-95: 283: 100.00
+	Hs
		957113 CCL19_HUMAN (17-91): 9.87e-22: 83: 31.17		TSG6_HUMAN (12-277): 2.95e-95: 283: 100.00
+	Hs
		134297 CCL21_HUMAN (23-91): 1.24e-18: 76.1: 28.77		TSG6_HUMAN (12-277): 2.95e-95: 283: 100.00
+	Hs
		234417 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		NRP2_HUMAN (132-276): 2.27e-34: 133: 28.38
+	Hs
		486349 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		PCOC2_HUMAN (135-271): 2.6e-32: 124: 29.93
+	Hs
		561754 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		PCOC2_HUMAN (135-271): 2.6e-32: 124: 29.93
+	Hs
		486217 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		BMP1_HUMAN (131-273): 9.48e-28: 114: 27.97
+	Hs
		486218 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CSPG2_HUMAN (33-137): 6.58e-17: 82.5: 29.73
+	Hs
		486313 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		HPLN3_HUMAN (33-129): 6.44e-17: 81.3: 37.76
+	Hs
		528230 CCL5_HUMAN (1-91): 4.43e-31: 106: 100.00		CSPG2_HUMAN (33-137): 6.58e-17: 82.5: 29.73
+	Hs
		530375 CCL8_HUMAN (1-90): 4.78e-31: 106: 36.96		CSPG2_HUMAN (33-137): 6.58e-17: 82.5: 29.73
+	Hs
		528198 CCL2_HUMAN (1-90): 2.17e-27: 97.3: 33.70		CSPG2_HUMAN (33-137): 6.58e-17: 82.5: 29.73
+	Hs
		134289 CCL21_HUMAN (23-91): 1.24e-18: 76.1: 28.77		CSPG2_HUMAN (33-137): 6.58e-17: 82.5: 29.73
+	Hs
		530374 CCL20_HUMAN (3-90): 5.27e-18: 73.4: 28.89		CSPG2_HUMAN (33-137): 6.58e-17: 82.5: 29.73